Indocyanine Green-Conjugated Superparamagnetic Iron Oxide Nanoworm for Multimodality Breast Cancer Imaging
Source abstract
Abstract
Breast cancer is the leading cause of cancer-associated deaths among women. Techniques for non-invasive breast cancer detection and imaging are urgently needed. Multimodality breast cancer imaging is attractive since it can integrate advantages from several modalities, enabling more accurate cancer detection. In order to accomplish this, indocyanine green (ICG)-conjugated superparamagnetic iron oxide nanoworm (NW-ICG) has been synthesized as a contrast agent. When evaluated in a spontaneous mouse breast cancer model, NW-ICG gave a large tumor to normal tissue contrasts in multiple imaging modalities including magnetic particle imaging, near-infrared fluorescence imaging, and photoacoustic imaging, providing more comprehensive detection and imaging of breast cancer. Thus, NW-ICGs are an attractive platform for non-invasive breast cancer diagnosis.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Characterization and Applications of Magnetic Nanoparticles · Nanoparticle-Based Drug Delivery · Photoacoustic and Ultrasonic Imaging
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, United States
Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan 48824, United States
Department of Electrical and Computer Engineering, Michigan State University, East Lansing, Michigan 48824, United States
Department of Biomedical Engineering, Michigan State University, East Lansing, Michigan 48824, United States
Funding
National Cancer Institute · Michigan State University · U.S. Department of Energy · National Science Foundation
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