Multifunctional BaMnLuGdF7: Yb/Er/Ho nanoparticles for in vivo tri-modal imaging
Source abstract
Abstract
Abstract Developing multifunctional bio-probes for tumor-imaging is greatly challenging and urgently demanded, which can offer comprehensive and accurate diagnostic information. Here, folic acid-modified Ba1.4Mn0.6Lu0.5Gd0.5F7: 20%Yb3+/0.2%Er3+/0.2%Ho3+ nanoparticles (abbreviated as BMLGF@FA) with a small size of ∼8 nm were designed and prepared for tumor-imaging. Through adopting the apropos metal ions and modifier, BMLGF@FA not only exhibited excellent red emission, superior X-ray absorption and strong magnetism, but also had tumor targeting ability and low toxicity. Further, it was successfully applied to in vivo tri-modal tumor imaging of upconversion fluorescence (UCL), magnetic resonance (MR) and X-ray computed tomography (CT). This work would be beneficial to develop a potential multimodality contrast agent for cancer clinical diagnosis.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Atomic and Subatomic Physics Research · Luminescence Properties of Advanced Materials · Inorganic Fluorides and Related Compounds
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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