journal article·2024-09-13Open access

Cyclodextrin-Based Nanogels for Stabilization and Sensing of Curcumin

Maria Antonietta Casulli, Ruyu Yan, Satomi Takeuchi, Andrea Cesari, Fabrizio Mancin, Takashi Hayashita, Takeshi Hashimoto, Irene Taurino

ACS Applied Nano Materials· Volume 7· Issue 17

Abstract

Curcumin (CUR), a polyphenolic substance from turmeric, displays diverse medicinal properties. However, its instability poses challenges in detection. Cyclodextrin-based nanogels (CyDngs) offer a transformative solution, enhancing CUR’s stability in aqueous solutions. Multisensing approaches involving fluorescence, electrochemistry, and NMR spectroscopy were employed, demonstrating CyDngs’ pivotal role in CUR detection. Langmuir analysis revealed a binding constant of 1.4 × 10 4 M –1 for CyDngs, highlighting their effectiveness over native β-CyDs. The study emphasized CyDngs’ superiority in stabilizing CUR and enabling reliable and sensitive detection with very diverse methods.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Curcumin's Biomedical Applications · Advancements in Transdermal Drug Delivery · Biochemical effects in animals

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Micro and Nano-Systems (MNS), Department of Electrical Engineering (ESAT)

Katholieke Universiteit Leuven (KU Leuven)

Graduate School of Science and Technology, Department of Materals and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554, Japan

Department of Chemistry and Industrial Chemistry, University of Pisa, via G. Moruzzi 13, 56124 Pisa, Italy

Department of Chemical Sciences, University of Padova, via Marzolo 1, 35131 Padova, Italy

Semiconductor Physics (HF), Department of Physics and Astronomy

Funding

Associazione Italiana per la Ricerca sul Cancro · H2020 Marie Sklodowska-Curie Actions · Japan Society for the Promotion of Science · Sophia University

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