journal article·2024-12-13

Area-Addressable ZnO Nanowire-Based Cold Cathode Transparent Flat-Panel X-ray Sources for Visual Intraoperative Radiotherapy

Song Kang, Guofu Zhang, Runze Zhan, Yuan Xu, Linghong Zhou, Shaozhi Deng, Ningsheng Xu, Jun Chen

ACS Applied Nano Materials· Volume 7· Issue 23
Publisher page

Abstract

X-ray intraoperative radiotherapy (IORT) is an important method for treating specific tumors. Area-addressable transparent flat-panel X-ray source can achieve selective-area radiotherapy and direct optical imaging guide, which could enhance the capability of the current IORT technique and has not been reported to date. In this paper, an area-addressable transparent flat-panel X-ray source was realized using zinc oxide (ZnO) nanowire field emitter arrays (FEAs) and an indium tin oxide (ITO) transparent anode. Planar-gate ZnO nanowire FEAs were fabricated and demonstrated a good addressing performance and uniform electron emission characteristics. A maximum anode current density of 884 μA/cm 2 was measured at one area under gate-addressed emission conditions, and the current fluctuation was approximately 5.8% in 2.5 h. The planar-gated ZnO nanowire FEAs were applied in the transparent flat-panel X-ray source. A radiation dose rate of 5.76 mGy/s was measured at the anode surface of the flat-panel X-ray source under the application of 40 kV anode voltages. The reported X-ray source device has potential applications in advanced intraoperative radiotherapy.
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Research context

OpenAlex topics: Luminescence Properties of Advanced Materials · Nanowire Synthesis and Applications · Photorefractive and Nonlinear Optics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

State Key Laboratory of Optoelectronic Materials and Technologies, Guangdong Province Key Laboratory of Display Material and Technology, School of Electronics and Information Technology, Sun Yat-Sen University, Guangzhou 510275, China

School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China

Funding

Guangdong Provincial Department of Science and Technology · National Key Research and Development Program of China · Special Project for Research and Development in Key areas of Guangdong Province · Fundamental Research Funds for the Central Universities · National Natural Science Foundation of China

References (27)

Show source-provided references
1. 10.1109/5.75725810.1109/5.757258 ↗
2. 10.1016/j.apsusc.2019.04.16910.1016/j.apsusc.2019.04.169 ↗
3. 10.1038/354056a010.1038/354056a0 ↗
4. 10.1039/D0TC05873D10.1039/D0TC05873D ↗
5. 10.1063/1.181237310.1063/1.1812373 ↗
6. 10.1021/acsami.5b0937410.1021/acsami.5b09374 ↗
7. 10.1049/el:1993106310.1049/el:19931063 ↗
8. 10.1063/1.165681010.1063/1.1656810 ↗
9. 10.1002/adma.20060127410.1002/adma.200601274 ↗
10. 10.1088/0957-4484/24/8/08520110.1088/0957-4484/24/8/085201 ↗
11. 10.1063/1.234582910.1063/1.2345829 ↗
12. 10.1016/j.carbon.2015.07.04410.1016/j.carbon.2015.07.044 ↗
13. 10.1109/ACCESS.2014.235175110.1109/ACCESS.2014.2351751 ↗
14. Billingsley, A.; Inscoe, C. R.; Xu, S.; Spronk, D.; Luo, Y.; Zhou, O.; Lu, J.; Lee, Y. Z. In Clinical Developments of a Stationary Head CT Using CNT X-ray Source Arrays, Medical Imaging 2023: Physics of Medical Imaging; SPIE, 2023; pp 835–841.10.1117/12.2654486 ↗
15. 10.1063/1.493800610.1063/1.4938006 ↗
16. 10.1109/TNS.2021.305100810.1109/TNS.2021.3051008 ↗
17. 10.1063/5.006133210.1063/5.0061332 ↗
18. 10.1109/TED.2023.326775710.1109/TED.2023.3267757 ↗
19. 10.3389/fonc.2017.0030010.3389/fonc.2017.00300 ↗
20. 10.3389/fonc.2018.0007410.3389/fonc.2018.00074 ↗
21. 10.1080/10463356.2008.1188341310.1080/10463356.2008.11883413 ↗
22. 10.1063/1.359526810.1063/1.3595268 ↗
23. 10.1063/1.482658710.1063/1.4826587 ↗
24. Bratsuk, A. V.; Simonov, A. A.; Taubin, M. L.; Chesnokov, D. A. In Miniature X-ray Emitters with Carbon Nanotube Cathodes for Radiotherapy, AIP Publishing Proceedings; AIP Publishing, 2018.10.1063/1.5095736 ↗
25. 10.1103/PhysRev.102.146410.1103/PhysRev.102.1464 ↗
26. 10.1109/TED.2019.295793210.1109/TED.2019.2957932 ↗
27. 10.1021/cg400318f10.1021/cg400318f ↗