journal article·2022-10

Glassy carbon electrode modified by gold nanofibers decorated iron metal–organic framework nanocomposite for voltammetric determination of acetaminophen

K. V. Kavya, Dinesh Muthu, Stella Varghese, Dhanaprabhu Pattappan, R. T. Rajendra Kumar, Yuvaraj Haldorai

Carbon Letters· Volume 32· Issue 6
Publisher page

Abstract

In this work, a nanocomposite containing gold (Au) nanofibers decorated iron-metal–organic framework (Fe-MOF) was successfully synthesized for electrochemical detection of acetaminophen (AAP). The as-synthesized Au@Fe-MOF nanocomposite was confirmed by various characterization techniques. Morphological analysis showed that the Au nanofibers with an average size of less than 10 nm were dispersed on the Fe-MOF. Cyclic voltammetric analysis showed that the Au@Fe-MOF nanocomposite showed well-defined redox peaks with higher current than that of GCE and Fe-MOF. The Au@Fe-MOF/GCE exhibited a linear range, sensitivity, and detection limit of 0.5–18 µM, 4.95 µM/µA/cm2, and 0.12 µM, respectively. The Au@Fe-MOF/GCE showed a very low response for the interference materials. The real sample analysis revealed that the Au@Fe-MOF/GCE showed good recovery towards the AAP in urine and paracetamol. Therefore, the developed sensor can be used for quality control of AAP.
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Research context

OpenAlex topics: Electrochemical sensors and biosensors · Analytical Methods in Pharmaceuticals · Electrochemical Analysis and Applications

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