Spatial regulation of synthetic and biological nanoparticles by DNA nanotechnology
Source abstract
Abstract
Nanoparticles are among the most fascinating materials because of their unique size-dependent properties. The spatial positioning of the nanoparticles with a nanoscale precision will greatly enhance their potential for use in the fabrication of functional materials and devices. Recently, the development of DNA nanotechnology has enabled the construction of two- and three-dimensional, precisely addressable nanostructures and devices based on DNA sequence design and programmable assembly. Advances in conjugating DNA with nanoparticles can bridge these two technologies and provide scientists with a new tool to study material transportation and energy transfer at a nanometer scale. In this review, we summarize the recent progress in this emerging research field, which includes not only the static arrangements of inorganic nanoparticles but also the dynamic regulation of organic and biological units at a nanometer scale. With the rapid development in this field, new challenges and new possibilities will emerge and bring about fruitful achievements with a significant impact on future work. DNA nanotechnology is a highly promising way to spatially arrange both synthetic and biological nanoparticles. As such, it holds out much potential for enhancing the fabrication of functional materials and devices. In this review, scientists from Tsinghua University and Shanghai Institute of Applied Physics in China summarize recent advances in this emerging field. They first review progress in the spatial regulation of nanoparticles by static DNA nanostructures, including the formation of plasmonic structures from metal nanoparticles and the regulation of reaction pathways for bio-inspired nanofactories. They also consider the dynamic regulation of nanoparticles using DNA, which enables the fabrication of devices whose structures can be spatially tuned. They then discuss the new concept of spatial regulation of DNA molecules on individual nanoparticles. Finally, they review future challenges in this field. Recent progress in spatial regulation of synthetic and biological nanoparticles by DNA nanotechnology has been summarized, including not only the static arrangement of inorganic nanoparticles but also the dynamic regulation of organic and biological units at a nanometer scale.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques · RNA Interference and Gene Delivery · Gold and Silver Nanoparticles Synthesis and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (94)
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