Self-healing ionic gelatin/glycerol hydrogels for strain sensing applications
Source abstract
Abstract
Abstract Soft sensing technologies have the potential to revolutionize wearable devices, haptic interfaces and robotic systems. However, there are numerous challenges in the deployment of these devices due to their poor resilience, high energy consumption, and omnidirectional strain responsivity. This work reports the development of a versatile ionic gelatin-glycerol hydrogel for soft sensing applications. The resulting sensing device is inexpensive and easy to manufacture, is self-healable at room temperature, can undergo strains of up to 454%, presents stability over long periods of time, and is biocompatible and biodegradable. This material is ideal for strain sensing applications, with a linear correlation coefficient R2 = 0.9971 and a pressure-insensitive conduction mechanism. The experimental results show the applicability of ionic hydrogels for wearable devices and soft robotic technologies for strain, humidity, and temperature sensing while being able to partially self-heal at room temperature.
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Research context
OpenAlex topics: Advanced Sensor and Energy Harvesting Materials · Dielectric materials and actuators · Conducting polymers and applications
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References (55)
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1. Amjadi, M., Kyung, K.-U., Park, I. & Sitti, M. Stretchable, skin-mountable, and wearable strain sensors and their potential applications: a review. Adv. Funct. Mater. 26, 1678–1698 (2016).10.1002/adfm.201504755 ↗
2. Rus, D. & Tolley, M. T. Design, fabrication and control of soft robots. Nature 521, 467–475 (2015).10.1038/nature14543 ↗
3. Mattmann, C., Clemens, F. & Tröster, G. Sensor for measuring strain in textile. Sensors 8, 3719–3732 (2008).10.3390/s8063719 ↗
4. Georgopoulou, A. & Clemens, F. Piezoresistive elastomer-based composite strain sensors and their applications. ACS Appl. Electron. Mater. 2, 1826–1842 (2020).10.1021/acsaelm.0c00278 ↗
5. Sareh, S. et al. Bio-inspired tactile sensor sleeve for surgical soft manipulators. In 2014 IEEE International Conference on Robotics and Automation (ICRA) 1454–1459 (IEEE, 2014).10.1109/ICRA.2014.6907043 ↗
6. Culha, U., Nurzaman, S. G., Clemens, F. & Iida, F. Svas3: strain vector aided sensorization of soft structures. Sensors 14, 12748–12770 (2014).10.3390/s140712748 ↗
7. Kramer, R. K., Majidi, C., Sahai, R. & Wood, R. J. Soft curvature sensors for joint angle proprioception. In 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems, 1919–1926 (IEEE, 2011).10.1109/IROS.2011.6094701 ↗
8. Russo, S. et al. Soft and stretchable sensor using biocompatible electrodes and liquid for medical applications. Soft Robot. 2, 146–154 (2015).10.1089/soro.2015.0011 ↗
9. Yang, C. & Suo, Z. Hydrogel ionotronics. Nat. Rev. Mater. 3, 125–142 (2018).10.1038/s41578-018-0018-7 ↗
10. Lee, Y., Song, W. J. & Sun, J.-Y. Hydrogel soft robotics. Mater. Today Phys. 15, 100258 (2020).10.1016/j.mtphys.2020.100258 ↗
11. Cai, G. et al. Extremely stretchable strain sensors based on conductive self-healing dynamic cross-links hydrogels for human-motion detection. Adv. Sci. 4, 1600190 (2017).10.1002/advs.201600190 ↗
12. Cheng, S., Narang, Y. S., Yang, C., Suo, Z. & Howe, R. D. Stick-on large-strain sensors for soft robots. Adv. Mater. Interfaces 6, 1900985 (2019).10.1002/admi.201900985 ↗
13. Tong, R. et al. Highly stretchable and compressible cellulose ionic hydrogels for flexible strain sensors. Biomacromolecules 20, 2096–2104 (2019).10.1021/acs.biomac.9b00322 ↗
14. Han, L. et al. Mussel-inspired adhesive and conductive hydrogel with long-lasting moisture and extreme temperature tolerance. Adv. Funct. Mater. 28, 1704195 (2018).10.1002/adfm.201704195 ↗
15. He, P. et al. Anti-freezing and moisturizing conductive hydrogels for strain sensing and moist-electric generation applications. J. Mater. Chem. A 8, 3109–3118 (2020).10.1039/C9TA12940E ↗
16. Shao, Z. et al. Degradable self-adhesive epidermal sensors prepared from conductive nanocomposite hydrogel. Nanoscale 12, 18771–18781 (2020).10.1039/D0NR04666C ↗
17. Huang, J. et al. A dual-mode wearable sensor based on bacterial cellulose reinforced hydrogels for highly sensitive strain/pressure sensing. Adv. Electron. Mater. 6, 1900934 (2020).10.1002/aelm.201900934 ↗
18. Hong, W., Zhao, X., Zhou, J. & Suo, Z. A theory of coupled diffusion and large deformation in polymeric gels. J. Mech. Phys. Solids 56, 1779–1793 (2008).10.1016/j.jmps.2007.11.010 ↗
19. Yuk, H. et al. Hydraulic hydrogel actuators and robots optically and sonically camouflaged in water. Nat. Commun. https://doi.org/10.1038/ncomms14230 (2017).10.1038/ncomms14230 ↗
20. Peng, X. & Wang, H. Shape changing hydrogels and their applications as soft actuators. J. Polym. Sci. Part B 56, 1314–1324 (2018).10.1002/polb.24724 ↗
21. Bennett, D. NaCl doping and the conductivity of agar phantoms. Mater. Sci. Eng. C31, 494–498 (2011).10.1016/j.msec.2010.08.018 ↗
22. Keplinger, C. et al. Stretchable, transparent, ionic conductors. Science 341, 984–987 (2013).10.1126/science.1240228 ↗
23. Liu, S. & Li, L. Ultrastretchable and self-healing double-network hydrogel for 3D printing and strain sensor. ACS Appl. Mater. Interfaces 9, 26429–26437 (2017).10.1021/acsami.7b07445 ↗
24. Tian, K. et al. 3D printing of transparent and conductive heterogeneous hydrogel–elastomer systems. Adv. Mater. 29, 1604827 (2017).10.1002/adma.201604827 ↗
25. Pan, X. et al. Ultraflexible self-healing guar gum-glycerol hydrogel with injectable, antifreeze, and strain-sensitive properties. ACS Biomater. Sci. Eng. 4, 3397–3404 (2018).10.1021/acsbiomaterials.8b00657 ↗
26. Sun, W., Schaffer, S., Dai, K., Yao, L. & Feinberg, A. 3D printing hydrogel-based soft and biohybrid actuators: a mini-review on fabrication techniques, applications, and challenges. Front. Robot. AI 8, 1–10 (2021).10.3389/frobt.2021.673533 ↗
27. Ouyang, L., Yao, R., Zhao, Y. & Sun, W. Effect of bioink properties on printability and cell viability for 3D bioplotting of embryonic stem cells. Biofabrication 8, 035020 (2016).10.1088/1758-5090/8/3/035020 ↗
28. Stevenson, M. et al. Development and characterization of ribose-crosslinked gelatin products prepared by indirect 3D printing. Food Hydrocoll. 96, 65–71 (2019).10.1016/j.foodhyd.2019.05.018 ↗
29. Sardesai, A. N. et al. Design and characterization of edible soft robotic candy actuators. MRS Adv. 3, 3003–3009 (2018).10.1557/adv.2018.557 ↗
30. Wang, J. et al. Self-healing and highly stretchable gelatin hydrogel for self-powered Strain sensor. ACS Appl. Mater. Interfaces 12, 1558–1566 (2020).10.1021/acsami.9b18646 ↗
31. Yan, X. et al. High strength and self-healable gelatin/polyacrylamide double network hydrogels. J. Mater. Chem. B 5, 7683–7691 (2017).10.1039/C7TB01780D ↗
32. Zhang, G., Lv, L., Deng, Y. & Wang, C. Self-healing gelatin hydrogels cross-linked by combining multiple hydrogen bonding and ionic coordination. Macromol. Rapid Commun. 38, 1–9 (2017).10.1002/marc.201700018 ↗
33. Sanwlani, S., Kumar, P. & Bohidar, H. B. Hydration of gelatin molecules in glycerol-water solvent and phase diagram of gelatin organogels. J. Phys. Chem. B 115, 7332–7340 (2011).10.1021/jp201877d ↗
34. Bigi, A., Panzavolta, S. & Rubini, K. Relationship between triple-helix content and mechanical properties of gelatin films. Biomaterials 25, 5675–5680 (2004).10.1016/j.biomaterials.2004.01.033 ↗
35. Peppas, N. A., Hilt, J. Z., Khademhosseini, A. & Langer, R. Hydrogels in biology and medicine: from molecular principles to bionanotechnology. Adv. Mater. 18, 1345–1360 (2006).10.1002/adma.200501612 ↗
36. Lukasik, K. V. & Ludescher, R. D. Molecular mobility in water and glycerol plasticized cold- and hot-cast gelatin films. Food Hydrocoll. 20, 96–105 (2006).10.1016/j.foodhyd.2005.03.007 ↗
37. Irvine, S. A. et al. Printing cell-laden gelatin constructs by freeform fabrication and enzymatic protein crosslinking. Biomed. Microdevices 17, 1–8 (2015).10.1007/s10544-014-9915-8 ↗
38. Tan, J. J. Y., Lee, C. P. & Hashimoto, M. Preheating of gelatin improves its printability with transglutaminase in direct ink writing 3D printing. Int. J. Bioprinting 6, 118–129 (2020).
39. Shintake, J., Sonar, H., Piskarev, E., Paik, J. & Floreano, D. Soft Pneumatic Gelatin Actuator for Edible Robotics 6221–6226 (IEEE, 2017).10.1109/IROS.2017.8206525 ↗
40. Han, L. et al. Mussel-inspired adhesive and conductive hydrogel with long-lasting moisture and extreme temperature tolerance. Adv. Funct. Mater. 28, 1–12 (2018).10.1002/adfm.201704195 ↗
41. Bergo, P. & Sobral, P. J. Effects of plasticizer on physical properties of pigskin gelatin films. Food Hydrocoll. 21, 1285–1289 (2007).10.1016/j.foodhyd.2006.09.014 ↗
42. Piazzoni, M. et al. Monolithic three-dimensional functionally graded hydrogels for bioinspired soft robots fabrication. Soft Robot. 00, 1–9 (2021).
43. Nagai, T., Kurita, A. & Shintake, J. Characterization of sustainable robotic materials and finite element analysis of soft actuators under biodegradation. Front. Robot. AI 8, 383 (2021).10.3389/frobt.2021.760485 ↗
44. Hughes, J. & Rus, D. Mechanically programmable, degradable ingestible soft actuators. 2020 3rd IEEE International Conference on Soft Robotics, RoboSoft 2020 836–843, https://doi.org/10.1109/RoboSoft48309.2020.9116001 (2020).10.1109/RoboSoft48309.2020.9116001 ↗
45. Hardman, D., Hughes, J., Thuruthel, T. G., Gilday, K. & Iida, F. 3D printable sensorized soft gelatin hydrogel for multi-material soft structures. IEEE Robot. Autom. Lett 6, 5269–5275 (2021).10.1109/LRA.2021.3072600 ↗
46. Baumgartner, M. et al. Resilient yet entirely degradable gelatin-based biogels for soft robots and electronics. Nat. Mater. 19, 1102–1109 (2020).10.1038/s41563-020-0699-3 ↗
47. Thuruthel, T. G., Hughes, J., Georgopoulou, A., Clemens, F. & Iida, F. Using redundant and disjoint time-variant soft robotic sensors for accurate static state estimation. IEEE Robot. Autom. Lett. 6, 2099–2105 (2021).10.1109/LRA.2021.3061399 ↗
48. Liu, Y. & Hsu, S. H. Synthesis and biomedical applications of self-healing hydrogels. Front. Chem. 6, 1–10 (2018).10.3389/fchem.2018.00001 ↗
49. Thangavel, G., Tan, M. W. M. & Lee, P. S. Advances in self-healing supramolecular soft materials and nanocomposites. Nano Converg. https://doi.org/10.1186/s40580-019-0199-9 (2019).10.1186/s40580-019-0199-9 ↗
50. Phadke, A. et al. Rapid self-healing hydrogels. Proc. Natl Acad. Sci. USA 109, 4383–4388 (2012).10.1073/pnas.1201122109 ↗
51. Xu, Y., Yang, H., Zhu, H., Jiang, L. & Yang, H. Self-healing gelatin-based shape memory hydrogels via quadruple hydrogen bonding and coordination crosslinking for controlled delivery of 5-fluorouracil. J. Biomater. Sci. Polym. Ed. 31, 712–728 (2020).10.1080/09205063.2020.1713711 ↗
52. Wang, J. et al. Self-healing and highly stretchable gelatin hydrogel for self-powered strain sensor. ACS Appl. Mater. Interfaces 12, 1558–1566 (2019).10.1021/acsami.9b18646 ↗
53. Li, C. H. & Zuo, J. L. Self-healing polymers based on coordination bonds. Adv. Mater. https://doi.org/10.1002/adma.201903762 (2020).10.1002/adma.201903762 ↗
54. Mao, J., Kondu, S., Ji, H. F. & McShane, M. J. Study of the near-neutral pH-sensitivity of chitosan/gelatin hydrogels by turbidimetry and microcantilever deflection. Biotechnol. Bioeng. 95, 333–341 (2006).10.1002/bit.20755 ↗
55. Terryn, S. et al. A review on self-healing polymers for soft robotics. Mater. Today 47, 187–205 (2021).10.1016/j.mattod.2021.01.009 ↗