article·2000-01-01

HISTOPATHOLOGY AND EEG STUDY ON THE FINE CARBON FIBER POWDER INJECTED INTO CEREBRAL TEMPORAL LOBE CORTEX OF THE RABBITS

Ke Fei

Abstract

After the fine carbon fiber powder was injected into the left cerebral temporal lobe cortex of the rabbits, the changes of cerebral histopathology and EEG were dynamically observed. Results showed that 1~104 weeks after the injecting, no neurological changes concerning with the implanting of the fine carbon fiber powder were found in the experimental rabbits. 1~2 weeks after the injecting, slight abnormal changes of the histopathology and EEG were found in the experimental group compared with the contrast group, but no significant differences were showed between them. 4 weeks after the injecting, no obvious injury changes were found under optical microscopes, but many slow waves (θ waves) were found in EEG, 8 weeks after the injecting, normal EEG was showed in the experimental group and contrast group. It can be concluded that the carbon fiber exhibits good histocompatibility with the cerebral temporal lobe cortex of rabbits.
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Research context

OpenAlex topics: Nerve injury and regeneration · Mesenchymal stem cell research · Electrospun Nanofibers in Biomedical Applications

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