journal article·2023-04-28Open access

Exploring the Bottom-Up Growth of Anisotropic Gold Nanoparticles from Substrate-Bound Seeds in Microfluidic Reactors

Gail A. Vinnacombe-Willson, Joy K. Lee, Naihao Chiang, Leonardo Scarabelli, Shouzheng Yue, Ruth Foley, Isaura Frost, Paul S. Weiss, Steven J. Jonas

ACS Applied Nano Materials· Volume 6· Issue 8

Abstract

We developed an unconventional seed-mediated in situ synthetic method, whereby gold nanostars are formed directly on the internal walls of microfluidic reactors. The dense plasmonic substrate coatings were grown in microfluidic channels with different geometries to elucidate the impacts of flow rate and profile on reagent consumption, product morphology, and density. Nanostar growth was found to occur in the flow-limited regime and our results highlight the possibility of creating shape gradients or incorporating multiple morphologies in the same microreactor, which is challenging to achieve with traditional self-assembly. The plasmonic-microfluidic platforms developed herein have implications for a broad range of applications, including cell culture/sorting, catalysis, sensing, and drug/gene delivery.
Source: europepmc · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Gold and Silver Nanoparticles Synthesis and Applications · Innovative Microfluidic and Catalytic Techniques Innovation · Nanomaterials and Printing Technologies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States

Department of Pediatrics, University of California, Los Angeles, Los Angeles, California 90095, United States

Department of Chemistry, University of Houston, Houston, Texas 77004, United States

Institute of Materials Science of Barcelona, ICMAB-CSIC, Campus UAB, Bellaterra 08193 Spain

Department of Bioengineering, University of California, Los Angeles, Los Angeles, California 90095, United States

Department of Materials Science and Engineering, University of California, Los Angeles, Los Angeles, California 90095, United States

California NanoSystems Institute, University of California, Los Angeles, Los Angeles, California 90095, United States

Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, California 90095, United States

Funding

Fundaci?n BBVA · NIH Office of the Director · University of California, Los Angeles · National Institute of Biomedical Imaging and Bioengineering · ?la Caixa? Foundation · Hyundai Hope On Wheels

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