Jammed interconnected bilayer emulsions as 3D-printable biological tissue mimics
Source abstract
Abstract
Here we present jammed interconnected bilayer emulsions (JIBEs) as a class of tissue-like materials with macroscopic scalability, comprising billions of bilayer-separated aqueous compartments per millilitre. These materials mimic the organizational structure and properties of biological tissues. Our self-assembly method generates up to decilitre-scale volumes of JIBEs within minutes. The process is highly adaptable to a wide range of amphiphiles, including lipids and block copolymers, providing flexibility in tailoring JIBEs for diverse applications. The jammed architecture of JIBEs imparts unique properties, such as direct extrusion 3D printability into aqueous solutions. Their membrane-bound structure allows functionalization with nanochannels, enabling the material to adopt the properties of the incorporated channels. In this study, we demonstrate three key features of JIBEs using distinct ion channels: tunable conductance, selective transport and memristance. We propose that functionalized JIBEs could unlock a broad range of applications, including separations, energy storage, neuromorphic computing, tissue engineering, drug delivery and soft robotics.
Source: europepmc · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Pickering emulsions and particle stabilization · Lipid Membrane Structure and Behavior · Block Copolymer Self-Assembly
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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