Multimodal scanning-probe quantum sensing of quantum materials
Source abstract
Abstract
Spin-defect-based quantum microscopy has recently made transformative advances in cutting-edge scientific research and technological innovation. The high sensitivity, high spatial resolution and excellent measurement modalities of quantum spin defects open up a range of opportunities at the forefront of condensed-matter physics research. Many of the advantages of this approach result from the quantum mechanical nature of the sensors, which offer functionalities that are not available with their classical counterparts. In this Review, we provide an overview of progress on scanning-probe nitrogen-vacancy quantum sensing research and its application to investigating the physics of emergent quantum materials with nanoscale spatial resolution. We also discuss quantum sensing platforms built on more recently discovered spin defects in one-dimensional and two-dimensional materials beyond nitrogen-vacancy centres. We conclude with an outlook on future directions and opportunities for these rapidly advancing quantum sensing technologies.
Source: europepmc · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Diamond and Carbon-based Materials Research · Quantum and electron transport phenomena · Electronic and Structural Properties of Oxides
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
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1. Degen, C. L., Reinhard, F. & Cappellaro, P. Quantum sensing. Rev. Mod. Phys. 89, 035002 (2017).10.1103/RevModPhys.89.035002 ↗
2. Casola, F., van der Sar, T. & Yacoby, A. Probing condensed matter physics with magnetometry based on nitrogen-vacancy centres in diamond. Nat. Rev. Mater. 3, 17088 (2018).10.1038/natrevmats.2017.88 ↗
3. Rovny, J. et al. Nanoscale diamond quantum sensors for many-body physics. Nat. Rev. Phys. 6, 753–768 (2024).10.1038/s42254-024-00775-4 ↗
4. Aslam, N. et al. Quantum sensors for biomedical applications. Nat. Rev. Phys. 5, 157–169 (2023).10.1038/s42254-023-00558-3 ↗
5. Crawford, S. E. et al. Quantum sensing for energy applications: review and perspective. Adv. Quantum Technol. 4, 2100049 (2021).10.1002/qute.202100049 ↗
6. Ye, J. & Zoller, P. Essay: quantum sensing with atomic, molecular, and optical platforms for fundamental physics. Phys. Rev. Lett. 132, 190001 (2024).10.1103/PhysRevLett.132.190001 ↗
7. Rondin, L. et al. Magnetometry with nitrogen-vacancy defects in diamond. Rep. Prog. Phys. 77, 056503 (2014).10.1088/0034-4885/77/5/056503 ↗
8. Doherty, M. W. et al. The nitrogen-vacancy colour centre in diamond. Phys. Rep. 528, 1–45 (2013).10.1016/j.physrep.2013.02.001 ↗
9. Koehl, W. F., Buckley, B. B., Heremans, F. J., Calusine, G. & Awschalom, D. D. Room temperature coherent control of defect spin qubits in silicon carbide. Nature 479, 84–87 (2011).10.1038/nature10562 ↗
10. Widmann, M. et al. Coherent control of single spins in silicon carbide at room temperature. Nat. Mater. 14, 164–168 (2015).10.1038/nmat4145 ↗
11. Bejarano, M. et al. Parametric magnon transduction to spin qubits. Sci. Adv. 10, eadi2042 (2024).10.1126/sciadv.adi2042 ↗
12. Chen, X. et al. Quantum sensing of room-temperature gerromagnetism in 2D van der Waals Fe3GaTe2 using divacancy spins in SiC. Adv. Funct. Mater. 35, 2413529 (2025).10.1002/adfm.202413529 ↗
13. Li, P. et al. Non-invasive bioinert room-temperature quantum sensor from silicon carbide qubits. Nat. Mater. 24, 1913–1919 (2025).10.1038/s41563-025-02382-9 ↗
14. Aharonovich, I., Englund, D. & Toth, M. Solid-state single-photon emitters. Nat. Photon. 10, 631–641 (2016).10.1038/nphoton.2016.186 ↗
15. Azzam, S. I., Parto, K. & Moody, G. Prospects and challenges of quantum emitters in 2D materials. Appl. Phys. Lett. 118, 240502 (2021).10.1063/5.0054116 ↗
16. Gottscholl, A. et al. Initialization and read-out of intrinsic spin defects in a van der Waals crystal at room temperature. Nat. Mater. 19, 540–545 (2020).10.1038/s41563-020-0619-6 ↗
17. Vaidya, S., Gao, X., Dikshit, S., Aharonovich, I. & Li, T. Quantum sensing and imaging with spin defects in hexagonal boron nitride. Adv. Phys. X 8, 2206049 (2023).
18. Rose, B. C. et al. Observation of an environmentally insensitive solid-state spin defect in diamond. Science 361, 60–63 (2018).10.1126/science.aao0290 ↗
19. Maletinsky, P. et al. A robust scanning diamond sensor for nanoscale imaging with single nitrogen-vacancy centres. Nat. Nanotechnol. 7, 320–324 (2012).10.1038/nnano.2012.50 ↗
20. Gross, I. et al. Real-space imaging of non-collinear antiferromagnetic order with a single-spin magnetometer. Nature 549, 252–256 (2017).10.1038/nature23656 ↗
21. Pelliccione, M. et al. Scanned probe imaging of nanoscale magnetism at cryogenic temperatures with a single-spin quantum sensor. Nat. Nanotechnol. 11, 700–705 (2016).10.1038/nnano.2016.68 ↗
22. Song, T. et al. Direct visualization of magnetic domains and moiré magnetism in twisted 2D magnets. Science 374, 1140–1144 (2021).10.1126/science.abj7478 ↗
23. Tan, A. K. C. et al. Revealing emergent magnetic charge in an antiferromagnet with diamond quantum magnetometry. Nat. Mater. 23, 205–211 (2024).10.1038/s41563-023-01737-4 ↗
24. Li, S. et al. Observation of stacking engineered magnetic phase transitions within moiré supercells of twisted van der Waals magnets. Nat. Commun. 15, 5712 (2024).10.1038/s41467-024-49942-2 ↗
25. Huxter, W. S., Sarott, M. F., Trassin, M. & Degen, C. L. Imaging ferroelectric domains with a single-spin scanning quantum sensor. Nat. Phys. 19, 644–648 (2023).10.1038/s41567-022-01921-4 ↗
26. Thiel, L. et al. Quantitative nanoscale vortex imaging using a cryogenic quantum magnetometer. Nat. Nanotechnol. 11, 677–681 (2016).10.1038/nnano.2016.63 ↗
27. Scholten, S. C. et al. Widefield quantum microscopy with nitrogen-vacancy centers in diamond: strengths, limitations, and prospects. J. Appl. Phys. 130, 150902 (2021).10.1063/5.0066733 ↗
28. Finco, A. et al. Imaging non-collinear antiferromagnetic textures via single spin relaxometry. Nat. Commun. 12, 767 (2021).10.1038/s41467-021-20995-x ↗
29. Kolkowitz, S. et al. Probing Johnson noise and ballistic transport in normal metals with a single-spin qubit. Science 347, 1129–1132 (2015).10.1126/science.aaa4298 ↗
30. McCullian, B. A. et al. Broadband multi-magnon relaxometry using a quantum spin sensor for high frequency ferromagnetic dynamics sensing. Nat. Commun. 11, 5229 (2020).10.1038/s41467-020-19121-0 ↗
31. van der Sar, T., Casola, F., Walsworth, R. & Yacoby, A. Nanometre-scale probing of spin waves using single electron spins. Nat. Commun. 6, 7886 (2015).10.1038/ncomms8886 ↗
32. Rovny, J. et al. Nanoscale covariance magnetometry with diamond quantum sensors. Science 378, 1301–1305 (2022).10.1126/science.ade9858 ↗
33. Huxter, W. S. et al. Scanning gradiometry with a single spin quantum magnetometer. Nat. Commun. 13, 3761 (2022).10.1038/s41467-022-31454-6 ↗
34. Qiu, Z., Hamo, A., Vool, U., Zhou, T. X. & Yacoby, A. Nanoscale electric field imaging with an ambient scanning quantum sensor microscope. npj Quantum Inf. 8, 107 (2022).10.1038/s41534-022-00622-3 ↗
35. Shields, B. J., Unterreithmeier, Q. P., de Leon, N. P., Park, H. & Lukin, M. D. Efficient readout of a single spin state in diamond via spin-to-charge conversion. Phys. Rev. Lett. 114, 136402 (2015).10.1103/PhysRevLett.114.136402 ↗
36. Hopper, D. A., Shulevitz, H. J. & Bassett, L. C. Spin readout techniques of the nitrogen-vacancy center in diamond. Micromachines 9, 437 (2018).10.3390/mi9090437 ↗
37. Laraoui, A. et al. Imaging thermal conductivity with nanoscale resolution using a scanning spin probe. Nat. Commun. 6, 8954 (2015).10.1038/ncomms9954 ↗
38. Lesik, M. et al. Magnetic measurements on micrometer-sized samples under high pressure using designed NV centers. Science 366, 1359–1362 (2019).10.1126/science.aaw4329 ↗
39. Yip, K. Y. et al. Measuring magnetic field texture in correlated electron systems under extreme conditions. Science 366, 1355–1359 (2019).10.1126/science.aaw4278 ↗
40. Hsieh, S. et al. Imaging stress and magnetism at high pressures using a nanoscale quantum sensor. Science 366, 1349–1354 (2019).10.1126/science.aaw4352 ↗
41. Bhattacharyya, P. et al. Imaging the Meissner effect in hydride superconductors using quantum sensors. Nature 627, 73–79 (2024).10.1038/s41586-024-07026-7 ↗
42. Broadway, D. A. et al. Imaging domain reversal in an ultrathin van der Waals ferromagnet. Adv. Mater. 32, 2003314 (2020).10.1002/adma.202003314 ↗
43. Li, Y. et al. Critical fluctuations and noise spectra in two-dimensional Fe3GeTe2 magnets. Nat. Commun. 16, 8585 (2025).10.1038/s41467-025-63578-w ↗
44. Huang, M. et al. Revealing intrinsic domains and fluctuations of moiré magnetism by a wide-field quantum microscope. Nat. Commun. 14, 5259 (2023).10.1038/s41467-023-40543-z ↗
45. Melendez, A. L. et al. Quantum sensing of broadband spin dynamics and magnon transport in antiferromagnets. Sci. Adv. 11, eadu9381 (2025).10.1126/sciadv.adu9381 ↗
46. Schlussel, Y. et al. Wide-field imaging of superconductor vortices with electron spins in diamond. Phys. Rev. Appl. 10, 034032 (2018).10.1103/PhysRevApplied.10.034032 ↗
47. Liu, Z. et al. Quantum noise spectroscopy of superconducting dynamics in thin film Bi2Sr2CaCu2O8+δ. Preprint at https://arxiv.org/abs/2502.04439 (2025).
48. Aslam, N. et al. Nanoscale nuclear magnetic resonance with chemical resolution. Science 357, 67–71 (2017).10.1126/science.aam8697 ↗
49. Glenn, D. R. et al. High-resolution magnetic resonance spectroscopy using a solid-state spin sensor. Nature 555, 351–354 (2018).10.1038/nature25781 ↗
50. Lovchinsky, I. et al. Magnetic resonance spectroscopy of an atomically thin material using a single-spin qubit. Science 355, 503–507 (2017).10.1126/science.aal2538 ↗
51. Wang, Y.-X. et al. Visualization of bulk and edge photocurrent flow in anisotropic Weyl semimetals. Nat. Phys. 19, 507–514 (2023).10.1038/s41567-022-01898-0 ↗
52. Bourgeois, E. et al. Photoelectric detection of electron spin resonance of nitrogen-vacancy centres in diamond. Nat. Commun. 6, 8577 (2015).10.1038/ncomms9577 ↗
53. Zhou, B. B. et al. Spatiotemporal mapping of a photocurrent vortex in monolayer MoS2 using diamond quantum sensors. Phys. Rev. X 10, 011003 (2020).
54. Zhang, X.-Y. et al. ac Susceptometry of 2D van der Waals magnets enabled by the coherent control of quantum sensors. PRX Quantum 2, 030352 (2021).10.1103/PRXQuantum.2.030352 ↗
55. Dasika, S., Markham, M. L. & Saha, K. Quantum diamond microscope method to determine AC susceptibility in micro-magnets. EPJ Quantum. Technol. 12, 85 (2025).10.1140/epjqt/s40507-025-00388-5 ↗
56. Kehayias, P. et al. Imaging crystal stress in diamond using ensembles of nitrogen-vacancy centers. Phys. Rev. B 100, 174103 (2019).10.1103/PhysRevB.100.174103 ↗
57. Trusheim, M. E. & Englund, D. Wide-field strain imaging with preferentially aligned nitrogen-vacancy centers in polycrystalline diamond. New J. Phys. 18, 123023 (2016).10.1088/1367-2630/aa5040 ↗
58. MacQuarrie, E. R., Gosavi, T. A., Jungwirth, N. R., Bhave, S. A. & Fuchs, G. D. Mechanical spin control of nitrogen-vacancy venters in diamond. Phys. Rev. Lett. 111, 227602 (2013).10.1103/PhysRevLett.111.227602 ↗
59. Balasubramanian, G. et al. Nanoscale imaging magnetometry with diamond spins under ambient conditions. Nature 455, 648–651 (2008).10.1038/nature07278 ↗
60. Tetienne, J.-P. et al. Nanoscale imaging and control of domain-wall hopping with a nitrogen-vacancy center microscope. Science 344, 1366–1369 (2014).10.1126/science.1250113 ↗
61. Hingant, T. et al. Measuring the magnetic moment density in patterned ultrathin ferromagnets with submicrometer resolution. Phys. Rev. Appl. 4, 014003 (2015).10.1103/PhysRevApplied.4.014003 ↗
62. Xu, Z. et al. Minimizing sensor-sample distances in scanning nitrogen-vacancy magnetometry. ACS Nano 19, 8255–8265 (2025).10.1021/acsnano.4c18460 ↗
63. Jelezko, F., Gaebel, T., Popa, I., Gruber, A. & Wrachtrup, J. Observation of coherent oscillations in a single electron spin. Phys. Rev. Lett. 92, 076401 (2004).10.1103/PhysRevLett.92.076401 ↗
64. Hanson, R., Dobrovitski, V. V., Feiguin, A. E., Gywat, O. & Awschalom, D. D. Coherent dynamics of a single spin interacting with an adjustable spin bath. Science 320, 352–355 (2008).10.1126/science.1155400 ↗
65. Wolfe, C. S. et al. Off-resonant manipulation of spins in diamond via precessing magnetization of a proximal ferromagnet. Phys. Rev. B 89, 180406 (2014).10.1103/PhysRevB.89.180406 ↗
66. Du, C. et al. Control and local measurement of the spin chemical potential in a magnetic insulator. Science 357, 195–198 (2017).10.1126/science.aak9611 ↗
67. Jarmola, A., Acosta, V. M., Jensen, K., Chemerisov, S. & Budker, D. Temperature- and magnetic-field-dependent longitudinal spin relaxation in nitrogen-vacancy ensembles in diamond. Phys. Rev. Lett. 108, 197601 (2012).10.1103/PhysRevLett.108.197601 ↗
68. Ariyaratne, A., Bluvstein, D., Myers, B. A. & Jayich, A. C. B. Nanoscale electrical conductivity imaging using a nitrogen-vacancy center in diamond. Nat. Commun. 9, 2406 (2018).10.1038/s41467-018-04798-1 ↗
69. Dolde, F. et al. Electric-field sensing using single diamond spins. Nat. Phys. 7, 459–463 (2011).10.1038/nphys1969 ↗
70. Yang, B. et al. Vector electrometry in a wide-gap-semiconductor device using a spin-ensemble quantum sensor. Phys. Rev. Appl. 14, 044049 (2020).10.1103/PhysRevApplied.14.044049 ↗
71. Li, R. et al. Nanoscale electrometry based on a magnetic-field-resistant spin sensor. Phys. Rev. Lett. 124, 247701 (2020).10.1103/PhysRevLett.124.247701 ↗
72. Bian, K. et al. Nanoscale electric-field imaging based on a quantum sensor and its charge-state control under ambient condition. Nat. Commun. 12, 2457 (2021).10.1038/s41467-021-22709-9 ↗
73. Mittiga, T. et al. Imaging the local charge environment of nitrogen-vacancy centers in diamond. Phys. Rev. Lett. 121, 246402 (2018).10.1103/PhysRevLett.121.246402 ↗
74. Palm, M. L. et al. Observation of current whirlpools in graphene at room temperature. Science 384, 465–469 (2024).10.1126/science.adj2167 ↗
75. Ku, M. J. H. et al. Imaging viscous flow of the Dirac fluid in graphene. Nature 583, 537–541 (2020).10.1038/s41586-020-2507-2 ↗
76. Jenkins, A. et al. Imaging the breakdown of Ohmic transport in graphene. Phys. Rev. Lett. 129, 087701 (2022).10.1103/PhysRevLett.129.087701 ↗
77. Andersen, T. I. et al. Electron-phonon instability in graphene revealed by global and local noise probes. Science 364, 154–157 (2019).10.1126/science.aaw2104 ↗
78. Monge, R. et al. Spin dynamics of a solid-state qubit in proximity to a superconductor. Nano Lett. 23, 422–428 (2023).10.1021/acs.nanolett.2c03250 ↗
79. Li, S. et al. Nanoscale observation and control of quasiparticle induced magnetic noise in a superconducting resonator. Phys. Rev. Lett. 136, 076004 (2026).10.1103/15c1-jjpy ↗
80. Acosta, V. M. et al. Temperature dependence of the nitrogen-vacancy magnetic resonance in diamond. Phys. Rev. Lett. 104, 070801 (2010).10.1103/PhysRevLett.104.070801 ↗
81. Kucsko, G. et al. Nanometre-scale thermometry in a living cell. Nature 500, 54–58 (2013).10.1038/nature12373 ↗
82. Wang, N. et al. Magnetic criticality enhanced hybrid nanodiamond thermometer under ambient conditions. Phys. Rev. X 8, 011042 (2018).
83. Toyli, D. M., de las Casas, C. F., Christle, D. J., Dobrovitski, V. V. & Awschalom, D. D. Fluorescence thermometry enhanced by the quantum coherence of single spins in diamond. Proc. Natl Acad. Sci. USA 110, 8417–8421 (2013).10.1073/pnas.1306825110 ↗
84. Doherty, M. W. et al. Electronic properties and metrology applications of the diamond NV− center under pressure. Phys. Rev. Lett. 112, 047601 (2014).10.1103/PhysRevLett.112.047601 ↗
85. Steele, L. G. et al. Optically detected magnetic resonance of nitrogen vacancies in a diamond anvil cell using designer diamond anvils. Appl. Phys. Lett. 111, 221903 (2017).10.1063/1.5004153 ↗
86. Ovartchaiyapong, P., Lee, K. W., Myers, B. A. & Jayich, A. C. B. Dynamic strain-mediated coupling of a single diamond spin to a mechanical resonator. Nat. Commun. 5, 4429 (2014).10.1038/ncomms5429 ↗
87. Teissier, J., Barfuss, A., Appel, P., Neu, E. & Maletinsky, P. Strain coupling of a nitrogen-vacancy center spin to a diamond mechanical oscillator. Phys. Rev. Lett. 113, 020503 (2014).10.1103/PhysRevLett.113.020503 ↗
88. Keimer, B. & Moore, J. E. The physics of quantum materials. Nat. Phys. 13, 1045–1055 (2017).10.1038/nphys4302 ↗
89. Dovzhenko, Y. et al. Magnetostatic twists in room-temperature skyrmions explored by nitrogen-vacancy center spin texture reconstruction. Nat. Commun. 9, 2712 (2018).10.1038/s41467-018-05158-9 ↗
90. Akhtar, W. et al. Current-induced nucleation and dynamics of skyrmions in a Co-based Heusler alloy. Phys. Rev. Appl. 11, 034066 (2019).10.1103/PhysRevApplied.11.034066 ↗
91. Tetienne, J.-P. et al. The nature of domain walls in ultrathin ferromagnets revealed by scanning nanomagnetometry. Nat. Commun. 6, 6733 (2015).10.1038/ncomms7733 ↗
92. McLaughlin, N. J. et al. Local control of a single nitrogen-vacancy center by nanoscale engineered magnetic domain wall motion. ACS Nano 17, 25689–25696 (2023).10.1021/acsnano.3c10633 ↗
93. Thiel, L. et al. Probing magnetism in 2D materials at the nanoscale with single-spin microscopy. Science 364, 973–976 (2019).10.1126/science.aav6926 ↗
94. Tschudin, M. A. et al. Imaging nanomagnetism and magnetic phase transitions in atomically thin CrSBr. Nat. Commun. 15, 6005 (2024).10.1038/s41467-024-49717-9 ↗
95. Högen, M. et al. Imaging nucleation and propagation of pinned domains in few-layer Fe5–xGeTe2. ACS Nano 17, 16879–16885 (2023).10.1021/acsnano.3c03825 ↗
96. Wang, Y.-X. et al. Configurable antiferromagnetic domains and lateral exchange bias in atomically thin CrPS4. Nat. Mater. 24, 1414–1423 (2025).10.1038/s41563-025-02259-x ↗
97. Sfeir, E. et al. Room temperature magnetic vortices in the van der Waals magnet Fe5GeTe2. Phys. Rev. Mater. 9, 114003 (2025).10.1103/v5zf-5z78 ↗
98. Burch, K. S., Mandrus, D. & Park, J.-G. Magnetism in two-dimensional van der Waals materials. Nature 563, 47–52 (2018).10.1038/s41586-018-0631-z ↗
99. Yang, H. et al. Two-dimensional materials prospects for non-volatile spintronic memories. Nature 606, 663–673 (2022).10.1038/s41586-022-04768-0 ↗
100. Gong, C. & Zhang, X. Two-dimensional magnetic crystals and emergent heterostructure devices. Science 363, eaav4450 (2019).10.1126/science.aav4450 ↗