A ‘Swiss army knife’ probe for metastatic cancers
Source abstract
Abstract
A nanosensor probe that combines a tumour-targeting peptide, a diagnostic reporter and an imaging contrast agent enables early diagnosis, precision imaging, disease stratification and downstream therapeutic response monitoring of metastatic cancer.
The source flagged this abstract for review. Check formulas and completeness against the original publication.
Source: openaire · Quality: needs review · Source record ↗
Source flags: short_text
Source flags: short_text
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced biosensing and bioanalysis techniques · RNA Interference and Gene Delivery
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (10)
Show source-provided references
1. Ofori, L. O. et al. ACS Chem. Biol. 10, 1977–1988 (2015).10.1021/acschembio.5b00205 ↗
2. Widen, J. C. et al. Nat. Biomed. Eng. 5, 264–277 (2021).10.1038/s41551-020-00616-6 ↗
3. Hunt, J. F., Rath, P., Rothschild, K. J. & Engelman, D. M. Biochemistry 36, 15177–15192 (1997).10.1021/bi970147b ↗
4. Weerakkody, D. et al. Proc. Natl Acad. Sci. USA 110, 5834–5839 (2013).10.1073/pnas.1303708110 ↗
5. Hao, L. et al. Nat. Mater. https://doi.org/10.1038/s41563-021-01042-y (2021).10.1038/s41563-021-01042-y ↗
6. Buss, C. G., Dudani, J. S., Akana, R. T. K., Fleming, H. E. & Bhatia, S. N. EBioMedicine 38, 248–256 (2018).10.1016/j.ebiom.2018.11.031 ↗
7. Dudani, J. S., Ibrahim, M., Kirkpatrick, J., Warren, A. D. & Bhatia, S. N. Proc. Natl Acad. Sci. USA 115, 8954–8959 (2018).10.1073/pnas.1805337115 ↗
8. Kirkpatrick, J. D. et al. Sci. Transl. Med. 12, eaaw0262 (2020).10.1126/scitranslmed.aaw0262 ↗
9. Kwong, G. A. et al. Nat. Biotechnol. 31, 63–70 (2013).10.1038/nbt.2464 ↗
10. Warren, A. D. et al. J. Am. Chem. Soc. 136, 13709–13714 (2014).10.1021/ja505676h ↗