Oncogenetic engagement with mechanosensing
Source abstract
Abstract
Reprogramming normal cells into tumour precursors involves complex reconditioning of the tissue microenvironment. Cumulative integration of genetic drivers with extrinsic mechanical inputs is now shown to engage YAP/TAZ to rewire cell mechanics and initiate tumorigenic reprogramming.
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Source: openaire · Quality: needs review · Source record ↗
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Research context
OpenAlex topics: Hippo pathway signaling and YAP/TAZ · Cellular Mechanics and Interactions · Microtubule and mitosis dynamics
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References (14)
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