journal article·2018-06

Smart delivery of vaccines

Cornelis J. M. Melief

Nature Materials· Volume 17· Issue 6
Publisher page

Abstract

A strategy to enhance antigen immunogenicity was developed by adsorption of polyethyleneimine on a mesoporous silica microrod vaccine for the presentation of tumour viruses and neoantigens, demonstrating their ability to drive anti-tumour immunity.
The source flagged this abstract for review. Check formulas and completeness against the original publication.
Source: openaire · Quality: needs review · Source record ↗
Source flags: short_text

Research context

OpenAlex topics: Immunotherapy and Immune Responses · CAR-T cell therapy research · RNA Interference and Gene Delivery

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (10)

Show source-provided references
1. Melief, C. J. M., van Hall, T., Arens, R., Ossendorp, F. & van der Burg, S. H. J. Clin. Invest. 125, 3401–3412 (2015).10.1172/JCI80009 ↗
2. Ott, P. A. et al. Nature 547, 217–220 (2017).10.1038/nature22991 ↗
3. Sahin, U. et al. Nature 547, 222–226 (2017).10.1038/nature23003 ↗
4. van Duikeren, S. et al. J. Immunol. 189, 3397–3403 (2012).10.4049/jimmunol.1201540 ↗
5. Li, A. W. et al. Nat. Mater. https://doi.org/10.1038/s41563-018-0028-2 (2018).10.1038/s41563-018-0028-2 ↗
6. Kim, J. et al. Nat. Biotechnol. 33, 64–72 (2015).10.1038/nbt.3071 ↗
7. Eickhoff, S. et al. Cell 162, 1322–1337 (2015).10.1016/j.cell.2015.08.004 ↗
8. Gerner, M. Y., Casey, K. A., Kastenmuller, W. & Germain, R. N. J. Exp. Med. 214, 3105–3122 (2017).10.1084/jem.20170335 ↗
9. Moynihan, K. D. et al. Nat. Med. 22, 1402–1410 (2016).10.1038/nm.4200 ↗
10. van der Burg, S. H., Arens, R., Ossendorp, F., van Hall, T. & Melief, C. J. M. Nat. Rev. Cancer 16, 219–233 (2016).10.1038/nrc.2016.16 ↗