journal article·2022-04

Efficient intracellular delivery of native proteins facilitated by preorganized guanidiniums on pillar[5]arene skeleton

Shuwen Guo, Qiaoxian Huang, Jianwen Wei, Shengpeng Wang, Yitao Wang, Leyong Wang, Ruibing Wang

Nano Today· Volume 43
Publisher page

Abstract

No abstract is available for this record. The assistant can identify its topic from the title, but cannot infer the study’s results.

Source: Not provided · Quality: missing

Research context

OpenAlex topics: RNA Interference and Gene Delivery · Supramolecular Self-Assembly in Materials · Advanced biosensing and bioanalysis techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (42)

Show source-provided references
1. Synthetic protein condensates that inducibly recruit and release protein activity in living cells10.1021/jacs.0c12375 ↗
2. Coordination-driven assembly of proteins and nucleic acids in a single architecture for carrier-free intracellular co-delivery10.1016/j.nantod.2021.101140 ↗
3. Receptor-mediated delivery of CRISPR-Cas9 endonuclease for cell-type-specific gene editing10.1021/jacs.8b01551 ↗
4. A coordinative dendrimer achieves excellent efficiency in cytosolic protein and peptide delivery10.1002/anie.201914970 ↗
5. Nanostructured mineral coatings stabilize proteins for therapeutic delivery10.1002/adma.201701255 ↗
6. Transduction methods for cytosolic delivery of Proteins and bioconjugates into living cells10.1002/adhm.201701040 ↗
7. Regulation of proteins to the cytosol using delivery systems with engineered polymer architecture10.1021/jacs.1c00258 ↗
8. Mitochondria-targeting, intracellular delivery of native proteins using biodegradable silica nanoparticles10.1002/anie.201901699 ↗
9. Engineered interactions with mesoporous silica facilitate intracellular delivery of proteins and gene editing10.1021/acs.nanolett.0c01387 ↗
10. Integrating combinatorial lipid nanoparticle and chemically modified protein for intracellular delivery and genome editing10.1021/acs.accounts.8b00493 ↗
11. Fast and efficient CRISPR/Cas9 genome editing in vivo enabled by bioreducible lipid and messenger RNA nanoparticles10.1002/adma.201902575 ↗
12. Serum insensitive, intranuclear protein delivery by the multipurpose cationic lipid Saint-210.1016/j.jconrel.2007.08.014 ↗
13. Optimizing charge switching in membrane lytic peptides for endosomal release of biomacromolecules10.1002/anie.202005887 ↗
14. Discovery and characterization of a peptide that enhances endosomal escape of delivered proteins in vitro and in vivo10.1021/jacs.5b05694 ↗
15. Potent protein delivery into mammalian cells via a supercharged polypeptide10.1021/jacs.8b10299 ↗
16. Reversible click chemistry for ultrafast and quantitative formation of protein–polymer nanoassembly and intracellular protein delivery10.1021/acsnano.9b04198 ↗
17. Polymers for cytosolic protein delivery10.1016/j.biomaterials.2019.119358 ↗
18. Direct cytosolic eelivery of proteins through coengineering of proteins and polymeric delivery vehicles10.1021/jacs.9b12759 ↗
19. Adhesive photoswitch: selective photochemical modulation of enzymes under physiological conditions10.1021/jacs.7b05151 ↗
20. Boronic acid-appended molecular glues for ATP-responsive activity modulation of enzymes10.1021/jacs.6b02664 ↗
21. Cell-surface interactions on arginine-rich cell-penetrating peptides allow for multiplex modes of internalization10.1021/acs.accounts.7b00221 ↗
22. Fifteen years of cell-penetrating, guanidinium-rich molecular transporters: basic science, research tools, and clinical applications10.1021/ar4000554 ↗
23. Direct cytosolic delivery of CRISPR/Cas9-ribonucleoprotein for efficient gene editing10.1021/acsnano.6b07600 ↗
24. General strategy for direct cytosolic protein delivery via protein–nanoparticle co-engineering10.1021/acsnano.7b02884 ↗
25. Sequence segregation improves non-covalent protein delivery10.1016/j.jconrel.2017.03.387 ↗
26. Synthetic protein mimics for functional protein delivery10.1021/acs.biomac.6b01685 ↗
27. Rational design of a polymer with robust efficacy for intracellular protein and peptide delivery10.1021/acs.nanolett.6b04955 ↗
28. Tailoring guanidyl-rich polymers for efficient cytosolic protein delivery10.1016/j.jconrel.2020.01.056 ↗
29. Intracellular photoactivation of caspase-3 by molecular glues for spatiotemporal apoptosis induction10.1021/jacs.0c01823 ↗
30. Applications of pillar[n]arene-based supramolecular assemblies10.1002/anie.201805884 ↗
31. Pillararene-based supramolecular functional materials10.1016/j.trechm.2020.07.004 ↗
32. Supramolecular amphiphiles based on host–guest molecular recognition motifs10.1021/cr5005315 ↗
33. Amphiphilic pillar[5]arene: synthesis, self-assembly in water, and application in bacterial cell agglutination10.1021/ja405237q ↗
34. Reversibly tunable lower critical solution temperature utilizing host–guest complexation of pillar[5]arene with triethylene oxide substituents10.1021/ja300989n ↗
35. Cationic pillararenes potently inhibit biofilm formation without affecting bacterial growth and viability10.1021/jacs.5b11834 ↗
36. Synthetic channel specifically inserts into the lipid bilayer of gram-positive bacteria but not that of mammalian erythrocytes10.1002/anie.201612093 ↗
37. Cationic vesicles based on amphiphilic pillar[5]arene capped with ferrocenium: a redox-responsive system for drug/siRNA Co-delivery10.1002/anie.201407272 ↗
38. Supramolecular delivery systems based on pillararenes10.1039/C8CC08252A ↗
39. Synthesis and bioactivity of guanidinium-functionalized pillar[5]arene as a biofilm disruptor10.1002/anie.202013975 ↗
40. Water-soluble flexible organic frameworks that include and deliver proteins10.1021/jacs.9b13263 ↗
41. Crystalline cyclophane–protein cage frameworks10.1021/acsnano.8b02856 ↗
42. Synergistic interplay of covalent and non-covalent interactions in reactive polymer nanoassembly facilitates intracellular delivery of antibodies10.1002/anie.202010412 ↗