Microenvironment-responsive nanocarriers for targeted bone disease therapy
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Abstract
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Research context
OpenAlex topics: Bone health and treatments · Bone Tissue Engineering Materials · Bone Metabolism and Diseases
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References (100+)
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1. Physiology of bone10.1159/000380991 ↗
2. Therapeutic approaches to bone diseases10.1126/science.289.5484.1508 ↗
3. Targeted nanomedicines for the treatment of bone disease and regeneration10.1002/med.21759 ↗
4. Development of bone targeting drugs10.3390/ijms18071345 ↗
5. Biofunctional polymer nanoparticles for intra-articular targeting and retention in cartilage10.1038/nmat2116 ↗
6. Polyethylene-glycol-modified single-walled carbon nanotubes for intra-articular delivery to chondrocytes10.1021/nn504537b ↗
7. Osteotropic nanoscale drug delivery systems based on small molecule bone-targeting moieties10.1016/j.nano.2016.08.015 ↗
8. Osteosarcoma risk in rats using PTH 1-3410.1016/S1043-2760(01)00489-1 ↗
9. Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research10.1002/jbmr.1998 ↗
10. Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research10.1359/jbmr.0707onj ↗
11. REVIEW: What the gastroenterologist should know about the gastrointestinal safety profiles of bisphosphonates10.1023/A:1016495221567 ↗
12. Ligand-installed nanocarriers toward precision therapy
13. Fabrication of physical and chemical crosslinked hydrogels for bone tissue engineering
14. Bone-targeted nanoparticle drug delivery system: an emerging strategy for bone-related disease
15. Bone-targeted biomaterials: Strategies and applications10.1016/j.cej.2022.137133 ↗
16. Rheumatoid arthritis microenvironment insights into treatment effect of nanomaterials10.1016/j.nantod.2021.101358 ↗
17. Targeted nanodelivery of drugs and diagnostics10.1016/j.nantod.2010.03.003 ↗
18. Self-assembled peptide-based nanostructures: Smart nanomaterials toward targeted drug delivery10.1016/j.nantod.2016.02.004 ↗
19. Multifunctional biomolecule nanostructures for cancer therapy10.1038/s41578-021-00315-x ↗
20. Engineered Nanoplatelets for Targeted Delivery of Plasminogen Activators to Reverse Thrombus in Multiple Mouse Thrombosis Models
21. Stimuli-Responsive Delivery of Growth Factors for Tissue Engineering10.1002/adhm.201901714 ↗
22. Biofilm Microenvironment-Responsive Nanotheranostics for Dual-Mode Imaging and Hypoxia-Relief-Enhanced Photodynamic Therapy of Bacterial Infections
23. Design of Diselenide-Bridged Hyaluronic Acid Nano-antioxidant for Efficient ROS Scavenging to Relieve Colitis10.1021/acsnano.2c05558 ↗
24. Multifunctional and stimuli-responsive nanocarriers for targeted therapeutic delivery10.1080/17425247.2021.1828339 ↗
25. Stimulus-Responsive Sequential Release Systems for Drug and Gene Delivery10.1016/j.nantod.2020.100914 ↗
26. Current multistage drug delivery systems based on the tumor microenvironment10.7150/thno.16684 ↗
27. Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment
28. Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics10.7150/thno.38069 ↗
29. Stimuli-responsive nanocarriers for delivery of bone therapeutics - Barriers and progresses10.1016/j.jconrel.2018.01.021 ↗
30. Bone-targeted pH-responsive cerium nanoparticles for anabolic therapy in osteoporosis
31. A Targeted and pH-Responsive Bortezomib Nanomedicine in the Treatment of Metastatic Bone Tumors10.1021/acsami.8b07527 ↗
32. Reactive Oxygen Species (ROS)-Responsive Biomaterials for the Treatment of Bone-Related Diseases
33. The contribution of solid-state NMR spectroscopy to understanding biomineralization: atomic and molecular structure of bone10.1016/j.jmr.2014.12.011 ↗
34. Mesenchymal Stem Cells: Cell Fate Decision to Osteoblast or Adipocyte and Application in Osteoporosis Treatment10.3390/ijms19020360 ↗
35. Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery10.1038/nrd4333 ↗
36. Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy10.1016/j.jsb.2003.08.006 ↗
37. Cartilage in normal and osteoarthritis conditions10.1016/j.berh.2008.02.001 ↗
38. The Effect of Antibody Size and Mechanical Loading on Solute Diffusion Through the Articular Surface of Cartilage10.1115/1.4037202 ↗
39. Electrostatic interactions enable rapid penetration, enhanced uptake and retention of intra-articular injected avidin in rat knee joints10.1002/jor.22630 ↗
40. Development of Targeted Nanoscale Drug Delivery System for Osteoarthritic Cartilage Tissue10.1166/jnn.2018.14311 ↗
41. Leveraging Electrostatic Interactions for Drug Delivery to the Joint10.1089/bioe.2020.0014 ↗
42. Nanotechnology controlled drug delivery for treating bone diseases10.1517/17425240903044935 ↗
43. Delivery of pharmaceutics to bone: nanotechnologies, high-throughput processing and in silico mathematical models10.22203/eCM.v031a23 ↗
44. Development of nanomaterials for bone-targeted drug delivery10.1016/j.drudis.2017.04.021 ↗
45. Role of Periostin in Adhesion and Migration of Bone Remodeling Cells10.1371/journal.pone.0147837 ↗
46. Optimizing the modification density of acid oligopeptides to enhance the bone-targeting activity of liposomes10.1016/j.compositesb.2022.110288 ↗
47. Demineralized Bone Matrix Scaffolds Modified by CBD-SDF-1α Promote Bone Regeneration via Recruiting Endogenous Stem Cells10.1021/acsami.6b08685 ↗
48. Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass10.1038/nm.2665 ↗
49. Controlled Release of Collagen-Binding SDF-1α Improves Cardiac Function after Myocardial Infarction by Recruiting Endogenous Stem Cells10.1038/srep26683 ↗
50. DMP1-targeted Cre expression in odontoblasts and osteocytes10.1177/154405910708600404 ↗
51. Targeting the alphavbeta3 integrin for small-animal PET/CT of osteolytic bone metastases10.2967/jnumed.109.067140 ↗
52. Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy10.1038/nm.3791 ↗
53. Cartilage-targeting drug delivery: can electrostatic interactions help10.1038/nrrheum.2016.210 ↗
54. Characterization of Intra-Cartilage Transport Properties of Cationic Peptide Carriers10.3791/61340 ↗
55. Targeted delivery of non-viral vectors to cartilage in vivo using a chondrocyte-homing peptide identified by phage display10.1016/j.biomaterials.2011.05.017 ↗
56. Recent advances in smart stimuli-responsive biomaterials for bone therapeutics and regeneration10.1038/s41413-021-00180-y ↗
57. Complete abrogation of key osteoclast markers with a membrane-anchored tissue inhibitor of metalloproteinase: a novel approach in the prevention of osteoclastogenesis10.1302/2046-3758.1111.BJR-2022-0147.R2 ↗
58. Osteoclast differentiation and activation10.1038/nature01658 ↗
59. Nanoparticle-cartilage interaction: pathology-based intra-articular drug delivery for osteoarthritis therapy
60. Reactive oxygen species, aging and articular cartilage homeostasis10.1016/j.freeradbiomed.2018.08.038 ↗
61. Nitric oxide nanosensors for predicting the development of osteoarthritis in rat model10.1021/acsami.7b06404 ↗
62. Targeting VEGF and Its Receptors for the Treatment of Osteoarthritis and Associated Pain10.1002/jbmr.2828 ↗
63. Microenvironment in subchondral bone: predominant regulator for the treatment of osteoarthritis10.1136/annrheumdis-2020-218089 ↗
64. Subchondral bone as a key target for osteoarthritis treatment10.1016/j.bcp.2011.09.018 ↗
65. Subchondral bone and osteoarthritis: biological and cellular aspects10.1007/s00198-012-2162-z ↗
66. MMP-2, MMP-9, TIMP-1 and TIMP-2 levels in patients with rheumatoid arthritis and psoriatic arthritis
67. Matrix Metalloproteinases and Synovial Joint Pathology
68. Oxidative stress in autoimmune rheumatic diseases10.1016/j.freeradbiomed.2018.05.086 ↗
69. Expression of proteinases and inflammatory cytokines in subchondral bone regions in the destructive joint of rheumatoid arthritis10.1093/rheumatology/40.3.247 ↗
70. Exploring the role of cathepsin in rheumatoid arthritis10.1016/j.sjbs.2021.09.014 ↗
71. Current Concepts of Osteomyelitis: From Pathologic Mechanisms to Advanced Research Methods10.1016/j.ajpath.2020.02.007 ↗
72. A dual-functional implant with an enzyme-responsive effect for bacterial infection therapy and tissue regeneration10.1039/C9BM01924C ↗
73. T. Yoshii, S. Magara, D. Miyai, H. Nishimura, E. Kuroki, S. Furudoi, T. Komori, C. Ohbayashi, Local levels of interleukin-1beta, -4, -6 and tumor necrosis factor alpha in an experimental model of murine osteomyelitis due to Staphylococcus aureus, Cytokine, 19 (2002) 59–65.10.1006/cyto.2002.1039 ↗
74. Targeting Endogenous Hydrogen Peroxide at Bone Defects Promotes Bone Repair
75. Immunomodulatory Effects of MSCs in Bone Healing10.3390/ijms20215467 ↗
76. Acidic microenvironment and bone pain in cancer-colonized bone
77. Research progress of bone-targeted drug delivery system on metastatic bone tumors10.1016/j.jconrel.2022.08.034 ↗
78. E-selectin-targeted porous silicon particle for nanoparticle delivery to the bone marrow
79. A cathepsin K inhibitor reduces breast cancer-induced osteolysis and skeletal tumor burden10.1158/0008-5472.CAN-06-3940 ↗
80. Osteoporosis10.1016/S0140-6736(18)32112-3 ↗
81. The "Three in One" Bone Repair Strategy for Osteoporotic Fractures
82. Role of proinflammatory cytokines in the pathophysiology of osteoarthritis10.1038/nrrheum.2010.196 ↗
83. Pro-inflammatory cytokines: The link between obesity and osteoarthritis10.1016/j.cytogfr.2018.10.002 ↗
84. Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome10.1074/jbc.M112.426254 ↗
85. Biphasic hierarchical extracellular matrix scaffold for osteochondral defect regeneration10.1016/j.joca.2017.12.001 ↗
86. The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis10.1155/2014/561459 ↗
87. Emerging regulators of the inflammatory process in osteoarthritis10.1038/nrrheum.2014.162 ↗
88. The association between knee temperature and pain in elders with osteoarthritis of the knee: a pilot study10.1046/j.1365-2648.2003.02629.x ↗
89. Novel treatment strategies in rheumatoid arthritis10.1016/S0140-6736(17)31491-5 ↗
90. zNovel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis10.1186/ar2106 ↗
91. The association of disease activity, pro-inflammatory cytokines, and neurotrophic factors with depression in patients with rheumatoid arthritis10.1016/j.bbi.2018.05.012 ↗
92. Oxidative stress in autoimmune rheumatic diseases10.1016/j.freeradbiomed.2018.05.086 ↗
93. Microvascular endothelial dysfunction in rheumatoid arthritis10.1038/s41584-018-0022-8 ↗
94. Targeting CD34+ cells of the inflamed synovial endothelium by guided nanoparticles for the treatment of rheumatoid arthritis10.1016/j.jaut.2019.05.016 ↗
95. Current Concepts of Osteomyelitis
96. Hollow mesoporous hydroxyapatite nanostructures; smart nanocarriers with high drug loading and controlled releasing features10.1016/j.ijpharm.2018.04.029 ↗
97. Carboxylated gold nanoparticles inhibit bone erosion by disturbing the acidification of an osteoclast absorption microenvironment10.1039/C9NR09698A ↗
98. Regulation of Inflammatory Response and Osteogenesis to Citrate-Based Biomaterials through Incorporation of Alkaline Fragments10.1002/adhm.202101590 ↗
99. Versatile effects of magnesium hydroxide nanoparticles in PLGA scaffold-mediated chondrogenesis10.1016/j.actbio.2018.04.022 ↗
100. Magnesium-organic framework-based stimuli-responsive systems that optimize the bone microenvironment for enhanced bone regeneration10.1016/j.cej.2020.125241 ↗