A bibliometric and visual analysis of the current status and future prospects of nanotechnology in fracture healing research(1995–2025)
Source abstract
Abstract
Abstract Research on nanotechnology for fracture healing is growing rapidly. A comprehensive bibliometric analysis of this field was still lacking. This study mapped the development trends and research hotspots. We collected articles and reviews on nanotechnology in fracture healing from 1995 to 2025. Data came from the Web of Science database. Bibliometric and visual analyses used VOSviewer, CiteSpace, and Sci Explorer. China published 359 papers, leading globally. The United States ranked second. India and Iran also contributed significantly. Chinese Academy of Sciences was the top institution. Soochow University and Sichuan University were highly productive. Neisiany Rasoul Esmaeely was the most prolific author. ACS Applied Materials & Interfaces published the most papers. Bioactive Materials had the highest impact. Five major research clusters emerged: bone regeneration, mechanical properties, in vitro studies, self-healing nanomaterials, and nanocoatings. Future hotspots include scaffolds, osteogenesis, and tissue engineering. Keyword burst analysis further suggested that delivery systems and tissue-engineering-based smart scaffolds may shape the next stage of this field, whereas clinical translation still faces challenges related to mechanical stability, degradation control, and complex pathological microenvironments. These findings help researchers understand the field and guide future studies.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Graphene and Nanomaterials Applications · Bone fractures and treatments
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine , No. 3, Kangxin Road, Xiqu Sub-district , Zhongshan , 528400 , Guangdong Province , China
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