Research progress in 3D bioprinting of skin: Challenges and opportunities
Source abstract
Abstract
Abstract This article investigates 3D bioprinting as an exciting solution to the problem of skin regeneration, emphasizing the possibility of eliminating the drawbacks of standard grafts. It covers the anatomy and functions of the skin and the need for synthetic skin for medical purposes. Existing substitutes are analysed, thereby exposing their drawbacks and constraints. This article discusses the concepts underpinning 3D bioprinting, bioinks used for the fabrication of the skin, and the manufacture of skin tissue constructs of several layers. The major issues are associated with vascularization and mechanical stability, while the forthcoming improvement of the integration of biomaterials, automation, and optimization based on AI will enable enhanced functionality and clinical applications. Skin 3D bioprinting offers a new perspective for the development of customizable and engineered skin grafts.
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Research context
OpenAlex topics: 3D Printing in Biomedical Research · Wound Healing and Treatments · Planarian Biology and Electrostimulation
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Mechanical Engineering, Maharishi Markandeshwar Engineering College, Maharishi Markandeshwar (Deemed to be University), Mullana , Ambala , India
Production Engineering Department, National Institute of Technology Agartala , Tripura, 799046 , India
Department of Machining, Assembly and Engineering Metrology, Faculty of Mechanical Engineering, VSB-Technical University of Ostrava , 70800 , Ostrava , Czech Republic
Department of Mechanical Engineering, School of Core Engineering, Faculty of Science, Technology & Architecture, Manipal University , Jaipur , Rajasthan , India
Industrial and Production Engineering, Dr. B R Ambedkar National Institute of Technology , Jalandhar , Punjab , India
School of Mechanical, Industrial & Aeronautical Engineering, University of the Witwatersrand , Johannesburg , Republic of South Africa
Department of Mechanical Engineering, Graphic Era (Deemed to be University) , Dehradun , Uttarakhand , India
Department of Biosciences, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences , Chennai , 602105 , India
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