DataVXACS Applied Nano MaterialsPaper
journal article·2020-02-28Open access

Single-Walled Carbon Nanotube Network Electrodes for the Detection of Fentanyl Citrate

Niklas Wester, Elsi Mynttinen, Jarkko Etula, Tuomas Lilius, Eija Kalso, Bjørn F. Mikladal, Qiang Zhang, Hua Jiang, Sami Sainio, Dennis Nordlund, Esko I. Kauppinen, Tomi Laurila, Jari Koskinen

ACS Applied Nano Materials· Volume 3· Issue 2
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Source abstract

Abstract

We prepare disposable single-walled carbon nanotube network electrodes for the detection of the potent opioid fentanyl, currently a leading cause for opioid overdose deaths in the USA. We show repeatable dry transfer of single-walled carbon nanotube (SWCNT) networks to produce robust electrodes. This process directly produces highly conductive SWCNT electrodes without the need for any further modifications required for conventional carbon electrodes. The realized electrode showed low background currents combined with spontaneous enrichment of fentanyl, resulting in a high signal-to-noise ratio. With this electrode, a detection limit of 11 nM and a linear range of 0.01–1 μM were found for fentanyl. In addition, selectivity is demonstrated in the presence of several common interferents.
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Research context

Nanomaterials

OpenAlex topics: Carbon Nanotubes in Composites · Neuroscience and Neural Engineering · Electrochemical sensors and biosensors

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Chemistry and Materials Science, Aalto University, Kemistintie 1, 02150 Espoo, Finland

Department of Electrical Engineering and Automation, Aalto University, Tietotie 3, 02150 Espoo, Finland

Department of Pharmacology, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland

Department of Clinical Pharmacology, University of Helsinki and Helsinki University Hospital, Tukholmankatu 8C, 00290 Helsinki, Finland

Pain Clinic, Department of Anesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 2A, 00290 Helsinki, Finland

Canatu Oy, Konalankuja 5, 00390 Helsinki, Finland

Department of Applied Physics, Aalto University School of Science, P.O. Box 15100, FI-00076 Aalto, Finland

Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, California 94025, United States

Funding

Tekes

References (57)

Show source-provided references
1. 10.1097/00000542-199902000-0003410.1097/00000542-199902000-00034 ↗
2. 10.15585/mmwr.mm6643e110.15585/mmwr.mm6643e1 ↗
3. 10.1016/j.drugalcdep.2016.11.03310.1016/j.drugalcdep.2016.11.033 ↗
4. 10.1093/jat/27.7.49910.1093/jat/27.7.499 ↗
5. 10.1093/jat/32.8.63910.1093/jat/32.8.639 ↗
6. 10.1016/j.drugalcdep.2017.08.02110.1016/j.drugalcdep.2017.08.021 ↗
7. 10.1016/j.neuropharm.2017.10.01610.1016/j.neuropharm.2017.10.016 ↗
8. 10.1016/j.electacta.2018.10.14810.1016/j.electacta.2018.10.148 ↗
9. 10.1016/j.snb.2005.02.02610.1016/j.snb.2005.02.026 ↗
10. 10.1016/0039-9140(94)00150-210.1016/0039-9140(94)00150-2 ↗
11. 10.1016/j.electacta.2013.02.04910.1016/j.electacta.2013.02.049 ↗
12. 10.1021/acs.analchem.9b0017610.1021/acs.analchem.9b00176 ↗
13. 10.1016/j.snb.2019.04.05310.1016/j.snb.2019.04.053 ↗
14. 10.1016/j.pmatsci.2017.04.01210.1016/j.pmatsci.2017.04.012 ↗
15. 10.1021/nl101680s10.1021/nl101680s ↗
16. 10.1038/nnano.2011.110.1038/nnano.2011.1 ↗
17. 10.1021/acsomega.9b0214710.1021/acsomega.9b02147 ↗
18. 10.1021/ja073360w10.1021/ja073360w ↗
19. 10.1016/j.molliq.2016.01.04310.1016/j.molliq.2016.01.043 ↗
20. 10.1016/j.snb.2013.06.02010.1016/j.snb.2013.06.020 ↗
21. 10.1021/acs.jpcc.9b0071410.1021/acs.jpcc.9b00714 ↗
22. 10.1021/acs.jpcc.5b0883210.1021/acs.jpcc.5b08832 ↗
23. 10.1021/nn200338r10.1021/nn200338r ↗
24. 10.1016/j.ces.2006.02.02010.1016/j.ces.2006.02.020 ↗
25. 10.1002/pssb.20066921010.1002/pssb.200669210 ↗
26. 10.1063/1.492224210.1063/1.4922242 ↗
27. 10.1134/S106378501611008010.1134/S1063785016110080 ↗
28. 10.1016/j.susc.2005.01.06210.1016/j.susc.2005.01.062 ↗
29. 10.1016/j.physrep.2004.10.00610.1016/j.physrep.2004.10.006 ↗
30. 10.1098/rsta.2004.144310.1098/rsta.2004.1443 ↗
31. 10.1021/nl080452q10.1021/nl080452q ↗
32. 10.1063/1.494867210.1063/1.4948672 ↗
33. 10.1103/PhysRevLett.95.22550710.1103/PhysRevLett.95.225507 ↗
34. 10.1016/S0009-2614(02)01620-210.1016/S0009-2614(02)01620-2 ↗
35. 10.1016/j.elspec.2013.03.00510.1016/j.elspec.2013.03.005 ↗
36. 10.1103/PhysRevB.52.314310.1103/PhysRevB.52.3143 ↗
37. 10.1016/0368-2048(88)80005-710.1016/0368-2048(88)80005-7 ↗
38. 10.1021/jp203741y10.1021/jp203741y ↗
39. Stöhr J. · 1992 · 2510.1007/978-3-662-02853-7 ↗
40. 10.1016/S0039-6028(87)80613-110.1016/S0039-6028(87)80613-1 ↗
41. 10.1116/1.58193810.1116/1.581938 ↗
42. 10.2136/sssaj2008.022810.2136/sssaj2008.0228 ↗
43. 10.1116/1.481305810.1116/1.4813058 ↗
44. 10.1016/j.jallcom.2006.01.12210.1016/j.jallcom.2006.01.122 ↗
45. 10.1088/0953-8984/27/4/04500210.1088/0953-8984/27/4/045002 ↗
46. 10.1021/ac00055a01710.1021/ac00055a017 ↗
47. 10.1021/ac00052a00710.1021/ac00052a007 ↗
48. 10.1016/j.electacta.2016.12.09910.1016/j.electacta.2016.12.099 ↗
49. 10.1016/j.electacta.2016.10.06310.1016/j.electacta.2016.10.063 ↗
50. 10.1039/j2968000097310.1039/j29680000973 ↗
51. 10.1016/j.snb.2008.03.01510.1016/j.snb.2008.03.015 ↗
52. 10.1053/j.jvca.2004.11.03910.1053/j.jvca.2004.11.039 ↗
53. 10.1016/j.jpba.2010.04.00410.1016/j.jpba.2010.04.004 ↗
54. 10.14429/dsj.61.6810.14429/dsj.61.68 ↗
55. 10.1016/S0731-7085(02)00345-X10.1016/S0731-7085(02)00345-X ↗
56. 10.1021/la049194c10.1021/la049194c ↗
57. ICH · Int. Conf. Harmon. · 2005 · 11