Gelatin nanoparticles: a potential candidate for medical applications
Source abstract
Abstract
Abstract Gelatin is a protein obtained from the hydrolysis of collagen. Gelatin is an attractive biodegradable material for use in nano-biotechnology and nano-pharmaceutics. Gelatin nanoparticles (NPs) have been widely used as drug and gene carrier to targeted sick tissues including cancer, tuberculosis, HIV infection along with the treatment of vasospasm and restenosis, due to its biocompatibility and biodegradability. For instance, coating with gelatin lowers the cytotoxicity of quantum dots. Moreover, gelatin NPs have the ability to cross the blood-brain barrier, hence proven as a promising candidate to target brain disorders. Macrophage targeting with gelatin NPs for remedy of different diseases is repeatedly reported in previous years. In tissue engineering gelatin is actively utilized for construction of biological and life-long 3D scaffolds for bio-artificial tissues and organ production. Gelatins have a wide range of potential applications which needs to be unraveled in more detail. This review is mainly focused on the applications of gelatin NPs in biomedical sciences.
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Research context
OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Bone Tissue Engineering Materials · Nanoparticles: synthesis and applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
1Department of Environmental Sciences, COMSATS Institute of Information Technology, Abbotabad, Pakistan
2Department of Physiology, Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan, Phone: +92-342-9620074, Fax: +92-5862519
3Department of Pharmacy, Kohat University of Science and Technology, Kohat, Pakistan
4Department of Biochemistry, Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan
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