journal article·2026-01-09

Recent developments in electrocatalytic oxidation of glycerol for value-added products synthesis

Lipeng Guo, Shengyin Shui, Linlin Zhang, Qianqian Hu, Shuting Xu, Zhefei Zhao, Huajun Zheng

Nanotechnology· Volume 37· Issue 1
Publisher page

Abstract

Abstract Glycerol, one of the important bio-platform molecules, is produced in large quantities as a byproduct in the biodiesel industry. It is imperative to convert glycerol into more value-added products (such as dihydroxyacetone, glyceraldehyde, glyceric acid, tartronic acid (TA), mesoxalic acid, glycolic acid, and formic acid) through various methods. Currently, the glycerol electrocatalytic oxidation reaction (GEOR) is one of the most promising routes owing to the mild operating conditions, efficient conversion, and high energy utilizations via coupling the cathodic reaction. In this review, we systematically introduce the recent advances in GEOR for the application of various products synthesis, focusing on the influence of reaction conditions, types of catalysts, and involved oxidation pathway and mechanisms. Furthermore, novelty coupled systems of GEOR and other cathodic reactions are summarized. Lastly, the subsistent challenges and perspectives are highlighted for GEOR.
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Research context

OpenAlex topics: Catalysis for Biomass Conversion · Electrocatalysts for Energy Conversion · Oxidative Organic Chemistry Reactions

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (100+)

Show source-provided references
1. Recent advances in glycerol valorization via electrooxidation: catalyst, mechanism and device10.1016/S1872-2067(22)64121-4 ↗
2. Sustainable catalytic oxidation of glycerol: a review10.1007/s10311-023-01608-z ↗
3. Anaerobic fermentation of glycerol: a path to economic viability for the biofuels industry10.1016/j.copbio.2007.05.002 ↗
4. Ethanol–diesel fuel blends—a review10.1016/j.biortech.2004.04.007 ↗
5. Glycerol transformation to value added C3 diols: reaction mechanism, kinetic, and engineering aspects10.1002/wene.159 ↗
6. Advancements in catalysts for glycerol oxidation via photo-/electrocatalysis: a comprehensive review of recent developments10.1039/D3GC03094F ↗
7. Two-step purification of glycerol as a value added by product from the biodiesel production process10.3389/fchem.2019.00774 ↗
8. The glycerin glut: options for the value-added conversion of crude glycerol resulting from biodiesel production10.1002/ep.10225 ↗
9. Hydrogen production from crude glycerol in an alkaline microbial electrolysis cell10.1016/j.ijhydene.2019.03.193 ↗
10. Selective oxidation of glycerol in a base-free aqueous solution: a short review10.1016/S1872-2067(19)63301-2 ↗
11. Distribution of methanol and catalysts between biodiesel and glycerin phases10.1002/aic.10385 ↗
12. Microwave assisted synthesis of glycerol carbonate from glycerol and urea10.1515/pac-2017-0303 ↗
13. Enzymatic route for selective glycerol oxidation using covalently immobilized laccases10.1016/j.enzmictec.2022.110168 ↗
14. Dihydroxyacetone induced autophagy in African trypanosomes10.4161/auto.4907 ↗
15. Polyamide fabric coated with a dihydroxyacetone-loaded chitosan hydrogel for a cosmeto-textile application10.1177/1528083719835762 ↗
16. A concise review of glycerol derivatives for use as fuel additives10.1016/j.heliyon.2023.e13041 ↗
17. Verfahren zur ueberfuehrung von hoeherwertigen alkoholen in niedrigerwertige
18. Glycerol as a source for fuels and chemicals by low-temperature catalytic processing10.1002/anie.200600212 ↗
19. One-pot electrocatalytic oxidation of glycerol to DHA10.1016/j.tetlet.2006.07.123 ↗
20. Platinum supported on H-mordenite: a highly efficient catalyst for selective hydrogenolysis of glycerol to 1,3-propanediol10.1021/acssuschemeng.5b01272 ↗
21. Enhancement of the valorization of renewable glycerol: the effects of the surfactant-enzyme interaction on the biocatalytic synthesis of glycerol carbonate10.1016/j.cattod.2016.02.038 ↗
22. One-pot biotransformation of glycerol into serinol catalysed by biocatalytic composites made of whole cells and immobilised enzymes10.1039/D0GC03918G ↗
23. WO3 photoanode with predominant exposure of {202} facets for enhanced selective oxidation of glycerol to glyceraldehyde10.1021/acsami.2c04608 ↗
24. Photoelectrocatalytic highly selective oxidation of glycerol to C3 products on Mo:BiVO4/NiOOH photoanodes10.1016/j.jelechem.2025.119019 ↗
25. Nanoscale high-entropy surface engineering promotes selective glycerol electro-oxidation to glycerate at high current density10.1038/s41565-025-01881-9 ↗
26. Recent advances in thermo-, photo-, and electrocatalytic glycerol oxidation10.1021/acscatal.8b01317 ↗
27. Toward glycerol biorefinery: metabolic engineering for the production of biofuels and chemicals from glycerol10.1186/s13068-016-0625-8 ↗
28. Challenges and strategies for optimization of glycerol steam reforming process10.1016/j.rser.2014.10.084 ↗
29. Catalytic valorization of glycerol to hydrogen and syngas10.1016/j.ijhydene.2012.12.079 ↗
30. High-purity propionate production from glycerol in mixed culture fermentation10.1016/j.biortech.2016.08.026 ↗
31. The potential of glycerol as a value-added commodity10.1016/j.cej.2016.03.012 ↗
32. Photoenzymatic hydroxylation of ethylbenzene catalyzed by unspecific peroxygenase: origin of enzyme inactivation and the impact of light intensity and temperature10.1002/cctc.201900610 ↗
33. Efficient photoelectrocatalysis of glycerol to dihydroxyacetone and synergistic hydrogen generation via dual oxidation pathways using Co-LDH/Bi2O3/TiO2 ternary array10.1021/acscatal.4c05193 ↗
34. Low energy photocatalytic glycerol conversion to high valuable products via Bi2O3 polymorphs in the presence of H2O210.1016/j.egyr.2020.08.029 ↗
35. Construction of a uniform Pt-Bi2O3 interface to enhance selective oxidation of glycerol to dihydroxyacetone10.1016/j.ces.2024.121113 ↗
36. Photo-oxidation of glycerol catalyzed by Cu/TiO210.3390/catal12080835 ↗
37. Bandgap engineering of TiO2 for enhanced selectivity in photoelectrochemical glycerol oxidation10.1002/admi.202400583 ↗
38. Multifunctional NiO/Ti3+–TiO2 for concurrent water reduction and glycerol oxidation to value added products by sunlight driven photocatalysis10.1039/D4TA06910B ↗
39. Near-infrared-featured broadband CO2 reduction with water to hydrocarbons by surface plasmon10.1038/s41467-023-35860-2 ↗
40. Copper indium sulfide quantum dots in photocatalysis10.1016/j.jcis.2023.01.107 ↗
41. A review of recent progress on electrocatalysts toward efficient glycerol electrooxidation10.1515/revce-2019-0013 ↗
42. Reaction engineering for high yield electrosynthesis: unraveling the impact of reaction conditions and conversion on methanol oxidation to formate10.1016/j.cej.2024.153000 ↗
43. Biphasic organic synthesis with continuous electro-flow10.1016/j.cogsc.2024.100896 ↗
44. Amorphous antimony oxide as reaction pathway modulator toward electrocatalytic glycerol oxidation for selective dihydroxyacetone production10.1016/j.apcatb.2023.123104 ↗
45. Adsorption configuration control on Pt-Bi2O3 for the oriented conversion of glycerol to glyceric acid via terminal hydroxyl oxidation10.1016/j.scib.2025.05.032 ↗
46. Regulating the competitive reaction pathway in glycerol conversion to lactic acid/glycolic acid selectively10.1016/j.jcat.2022.07.003 ↗
47. Electrochemical co-upgrading CO2 and glycerol for selective formate production with 190% overall Faradaic efficiency10.26599/NR.2025.94907399 ↗
48. Facilitating OH* generation on atomic Pd–Cu dual sites towards efficient glycerol electrooxidation to formate10.1002/anie.202425006 ↗
49. Controlled electrocatalytic glycerol upgrading to glyceraldehyde in near neutral media by cobalt oxide lattice activation10.1002/anie.202505059 ↗
50. Glycerol aerobic oxidation to glyceric acid over Pt/hydrotalcite catalysts at room temperature10.1016/j.scib.2019.10.003 ↗
51. Mechanistic aspects of glycerol electrooxidation on Pt(111) electrode in alkaline media10.1016/j.elecom.2017.11.027 ↗
52. Highly selective electro-oxidation of glycerol to dihydroxyacetone on platinum in the presence of bismuth10.1021/cs200599g ↗
53. Coproducing value-added chemicals and hydrogen with electrocatalytic glycerol oxidation technology: experimental and techno-economic investigations10.1021/acssuschemeng.7b00868 ↗
54. Electrocatalytic oxidation of glycerol to value-added compounds on Pd nanocrystals10.1021/acsanm.3c01236 ↗
55. Pd/CNT catalysts for glycerol electro-oxidation: effect of Pd loading on production of valuable chemical products10.1002/elan.201900611 ↗
56. Selective electro-oxidation of glycerol over Pd and Pt@Pd nanocubes10.1016/j.elecom.2018.04.012 ↗
57. Replacing oxygen evolution reaction by glycerol electrooxidation on Rh modified Ni(OH)2/C for energy-efficient hydrogen production10.1016/j.ijhydene.2023.04.267 ↗
58. Ultrathin RhCu bimetallenes for the selective electro-oxidation of glycerol10.1016/j.cej.2024.148960 ↗
59. The support influence of Au-based catalysts in glycerin selective oxidation to glyceric acid10.1002/jctb.7234 ↗
60. Electrosynthesis of glyceric acid from glycerol oxidation on Au–CeO2/CNT catalyst10.1016/j.jre.2024.04.010 ↗
61. Selective electro-oxidation of glycerol over Au supported on extended poly(4-vinylpyridine) functionalized grapheme10.1016/j.apcatb.2014.11.009 ↗
62. High DHA selectivity and low-cost electrode for glycerol oxidation: CuO regulates MnO2 electron density to promote DHA desorption10.1016/j.apcatb.2024.123986 ↗
63. Controlled galvanic decoration boosting catalysis: enhanced glycerol electro-oxidation at Cu/Ni modified macroporous films10.1016/j.ijhydene.2020.10.004 ↗
64. Electrochemical oxidation of glycerol to hydroxypyruvic acid on cobalt (oxy)hydroxide by high-valent cobalt redox centers10.1016/j.apcatb.2022.121247 ↗
65. Operando mechanistic studies of selective oxidation of glycerol to dihydroxyacetone over amorphous cobalt oxide10.1016/j.apcatb.2021.120723 ↗
66. Studies of the reaction products resulted from glycerol electrooxidation on Ni-based materials in alkaline medium10.1016/j.electacta.2013.11.127 ↗
67. Electrocatalytic glycerol upgrading into glyceric acid on Ni3Sn intermetallic compound10.1002/smll.202401872 ↗
68. Modification of nickel surfaces by bismuth: effect on electrochemical activity and selectivity toward glycerol10.1021/acsami.9b22378 ↗
69. Improved utilisation of renewable resources: new important derivatives of glycerol10.1039/B710561D ↗
70. Detection of 1,3-dihydroxyacetone by tris(2,2′-bipyridine)ruthenium(II) electrochemiluminescence10.1007/s00216-017-0833-5 ↗
71. Catalytic conversion of biodiesel derived raw glycerol to value added products10.1016/j.rser.2014.08.031 ↗
72. Dihydroxyacetone, the active browning ingredient in sunless tanning lotions, induces DNA damage, cell-cycle block and apoptosis in cultured HaCaT keratinocytes10.1016/j.mrgentox.2004.03.002 ↗
73. Effect of Co-catalyst on the selective electrooxidation of glycerol over ruthenium-based nanomaterials10.1002/celc.201600406 ↗
74. Seed-mediated synthesis of PtxAuy@Ag electrocatalysts for the selective oxidation of glycerol10.1016/j.apcatb.2019.01.009 ↗
75. Electro-oxidation of glycerol by tetrametallic platinum-gold–palladium-silver nanoparticles10.1007/s10800-020-01426-z ↗
76. Selective electro-oxidation of glycerol to dihydroxyacetone by a non-precious electrocatalyst—CuO10.1016/j.apcatb.2019.118543 ↗
77. Earth-abundant manganese oxide nanoneedle as highly efficient electrocatalyst for selective glycerol electro-oxidation to dihydroxyacetone10.1016/j.jcat.2021.09.005 ↗
78. Tuning selectivity and activity of the electrochemical glycerol oxidation reaction by manipulating morphology and exposed facet of spinel cobalt oxides10.1016/j.jcat.2023.05.010 ↗
79. Highly selective transformation of glycerol to dihydroxyacetone without using oxidants by a PtSb/C-catalyzed electrooxidation process10.1039/C5GC02865E ↗
80. Synthesis and characterization of supported Pd catalysts for potential application in glycerol electro-oxidation10.3390/catal12020192 ↗
81. Glycerol electro-oxidation to dihydroxyacetone on phosphorous-doped Pd/CNT nanoparticles in alkaline medium10.1016/j.catcom.2020.105964 ↗
82. Selective electro-oxidation of glycerol to dihydroxyacetone by PtAg skeletons10.1021/acsami.9b09431 ↗
83. Nitrogen-phosphorous co-doped palladium electrocatalyst for glycerol electro-oxidation reaction (GEOR): an efficient system for mesoxalic acid and dihydroxyacetone production10.1016/j.fuel.2022.126471 ↗
84. How to cross-link gelatin: the effect of glutaraldehyde and glyceraldehyde on the hydrogel properties10.1021/acsapm.3c01676 ↗
85. Optimizing d-mannose and glyceraldehyde concentrations as glucose preservatives without clinically affecting biochemical test results10.1016/j.plabm.2024.e00388 ↗
86. Glycerol to glyceraldehyde oxidation reaction over Pt-based catalysts under base-free conditions10.3389/fchem.2019.00156 ↗
87. Development of bismuth-modified PtPd nanocatalysts for the electrochemical reforming of polyols into hydrogen and value-added chemicals10.1002/celc.201600147 ↗
88. Product distribution of glycerol electro-oxidation over platinum-ceria/graphene nanosheet10.5796/electrochemistry.18-00048 ↗
89. Sustainable conversion of glycerol into value-added chemicals by selective electro-oxidation on Pt-based catalysts10.1002/celc.201800309 ↗
90. The electrochemical reforming of glycerol at Pd nanocrystals modified ultrathin NiO nanoplates hybrids: an efficient system for glyceraldehyde and hydrogen coproduction10.1007/s12274-021-3829-6 ↗
91. Insights into the selectivity to glyceric acid and lactic acid from biomass: reaction mechanism and temperature effect10.1016/j.cej.2024.153038 ↗
92. Efficient conversion of glycerol into high value-added chemicals by partial oxidation10.1002/aocs.12440 ↗
93. Electrochemical valorisation of glycerol10.1002/cssc.201200335 ↗
94. Role of Au-TiO2 interfacial sites in enhancing the electrocatalytic glycerol oxidation performance10.1016/j.elecom.2018.09.004 ↗
95. Electrocatalytic selective oxidation of glycerol to glyceric acid over efficient Pt/CNTs-CeO2 catalysts10.1016/j.matlet.2022.132658 ↗
96. Glycerol electro-oxidation in alkaline medium with Pt-Fe/C electrocatalysts synthesized by the polyol method: increased selectivity and activity provided by less expensive catalysts10.3390/nano13071173 ↗
97. Pulse potential mediated selectivity for the electrocatalytic oxidation of glycerol to glyceric acid10.1038/s41467-024-46752-4 ↗
98. Copper-modified gold nanoparticles as highly selective catalysts for glycerol electro-oxidation in alkaline solution10.1002/cctc.201600725 ↗
99. Selective glycerol-to-glycerate electro-oxidation on cerium-modified Pt/C nanocatalyst in an alkaline direct alcohol fuel cell: cogeneration of energy and value-added products10.1002/celc.202300555 ↗
100. Bi-modified Pt electrodes toward glycerol electrooxidation in alkaline solution: effects on activity and selectivity10.1021/acscatal.9b00190 ↗