DataVXACS Applied Nano MaterialsPaper
journal article·2024-03-08

Aptamers Adsorbed on WSe2 Nanosheets in a Label-Free Colorimetric Aptasensor for Ochratoxin A

Jiaojiao Zhou, Yuantao Liu, Xuqin Lv, Jilai Jia, Xiaoping Du, Jiangling He, Fang Xie, Zia-ud Din, Jie Cai

ACS Applied Nano Materials· Volume 7· Issue 5
Publisher page
Source abstract

Abstract

Ochratoxin A (OTA) poses a great threat to human health, and its rapid detection has drawn wide concerns in agri-food product risk assessment. Herein, on the basis of the aptamer-enhanced peroxidase-mimetic property of two-dimensional few-layer tungsten diselenide (WSe 2 ) nanosheets, a simple label-free colorimetric aptasensor is presented for OTA detection. The enzymatic mimic property of the WSe 2 nanosheets could be enhanced through aptamer adsorption because of the enhanced affinity of WSe 2 nanosheets to 3,3′,5,5′-tetramethylbenzidine. A good linear relationship was obtained in the range from 0.5 to 50 ng/mL, and the limit of detection for OTA was 0.16 ng/mL. The performance of this strategy was comparable to previous strategies for OTA determination. Further, this colorimetric aptasensor displayed satisfying specificity and stability in a complex food matrix including both red wine and wheat flour samples. Hence, the results of this study suggest potential applications of the aptasensor to detect mycotoxins in different agri-food products.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Advanced biosensing and bioanalysis techniques · Advanced Nanomaterials in Catalysis · Carbon and Quantum Dots Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

National R&D Center for Se-rich Agricultural Products Processing, School of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, China

Key Laboratory for Deep Processing of Major Grain and Oil, Ministry of Education, Hubei Key Laboratory for Processing and Transformation of Agricultural Products, Wuhan Polytechnic University, Wuhan 430023, China

Ankang R&D Center for Se-enriched Products, Key Laboratory of Se-enriched Products Development and Quality Control, Ministry of Agriculture and Rural Affairs, Ankang, Shaanxi 725000, China

Department of Food Science and Nutrition, Women University Swabi, Khyber Pakhtunkhawa, Swabi 23430, Pakistan

Funding

Research and Innovation Initiatives of WHPU · Key Laboratory of Se-enriched Products Development and Quality Control

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