journal article·2024-02-23

Nanomodulators That Target Alzheimer’s Disease: A Review

Nibedita Pradhan, Nihar Ranjan Jana

ACS Applied Nano Materials· Volume 7· Issue 4
Publisher page

Abstract

The vastness and multidimensional adversity of Alzheimer’s disease (AD) impede the outgrowth of its therapeutic research. Needless to say, the application of nanoscience has amplified the progress of prophylaxis and therapeutics development for AD. In this Review, we will elaborate on the advancement of a nanoparticle-based alternative therapeutic targeting AD in terms of design, approach, mechanism of action, and limitations associated with their clinical availability. So far, the blood–brain barrier (BBB) is one of the major hurdles for the clinical application of drugs for any neurodegenerative disease. Here, we will focus on the current state-of-the-art of nanoparticle-based therapeutics for crossing the BBB.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Alzheimer's disease research and treatments · Advanced Nanomaterials in Catalysis · Nanocluster Synthesis and Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Life Sciences, Kristu Jayanti College (Autonomous), Bangalore 560077, India

School of Bioscience, Indian Institute of Technology Kharagpur, Kharagpur 721302, India

Funding

Science and Engineering Research Board

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