journal article·2024-05-24

Stimulus-Responsive Bioactive Hydrogels in Diabetic Wound Healing

Guo Xu, Penghong Xu, Bingbing Gao, Jianlin Chu, Bingfang He

ACS Applied Nano Materials· Volume 7· Issue 10
Publisher page

Abstract

Diabetic wound infection has always been a huge threat to human’s healthcare, and most of the existing therapies have reduced efficacy, drug resistance and toxic side effects. Therefore, there is an urgent need to develop innovative therapeutic strategies for diabetic wound management. At present, the intelligence of stimulus-responsive bioactive hydrogels in diabetic wound healing has received extensive attention. This intelligence is mainly reflected in the on-demand release of active substances in response to physical, chemical or biological stimuli. This paper focuses on the potential of various stimulus-responsive bioactive hydrogels and their biological applications in diabetic wound healing, and briefly discusses the factors of slow diabetic wound healing and the preparation methods of smart bioactive hydrogels. Finally, the future development of stimulus-responsive bioactive hydrogels in the further management of diabetic wounds is presented.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Wound Healing and Treatments · Hydrogels: synthesis, properties, applications · Nerve injury and regeneration

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China

School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211816, China

Funding

the National Key Research and Development Program of China · the Jiangsu Synergetic Innovation Center for Advanced Bio-Manufacture · the Discipline Fund of Nanjing Tech University School of Pharmaceutical Sciences · the Nanjing Tech University Teaching Reform Project · the National Natural Science Foundation of China

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