DataVXACS Applied Nano MaterialsPaper
journal article·2023-09-22

Electrochemical Sensing of Uric Acid with Zinc Oxide Nanorods Decorated with Copper Oxide Nanoseeds

Sakeena Masrat, Vandana Nagal, Marya Khan, Akil Ahmad, Mohammed B. Alshammari, Shamshad Alam, Umesh T. Nakate, Byeong-il Lee, Prabhash Mishra, Kiesar Sideeq Bhat, Rafiq Ahmad

ACS Applied Nano Materials· Volume 6· Issue 18
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Source abstract

Abstract

The use of hybrid nanostructured nanomaterials in sensor development has the potential to overcome the sensitivity issue due to the combination of different nanoscale features of the desired nanomaterials that are accumulated together and offer entirely different characteristics. The sensitive quantification of biomolecules is required for early disease diagnosis. Herein, a hybrid (zinc oxide nanorods modified with copper oxide nanoseeds (ZnO NRs-CuO NSs)) nanostructured nanomaterial-integrated sensor that detects uric acid (UA) is reported. A low-temperature solution-based method was described for ZnO NR and ZnO NR-CuO NS hybrid nanomaterial syntheses. The use of the ZnO NR-CuO NS hybrid nanomaterial resulted in ultra-high sensitivity (1477.88 μA/mM cm 2 ) toward UA detection using the differential pulse voltammetry (DPV) technique. DPV resulted in ∼7.7 times better sensitivity compared to cyclic voltammetry (CV)-measured sensitivity (187.32 μA/mM cm 2 ). The surface modification of ZnO NRs with CuO NS “hybrid nanostructures” showed a significant impact and synergistic effect that enhanced the sensing performance. Furthermore, selectivity, stability, fabrication reproducibility, and applicability in the real sample are other crucial factors of this ZnO NR-CuO NS hybrid nanomaterial-based UA sensor.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Electrochemical sensors and biosensors · Electrochemical Analysis and Applications · Analytical Chemistry and Sensors

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Centre for Nanoscience and Nanotechnology, Jamia Millia Islamia, New Delhi110025, India

Department of Physics, Indian Institute of Technology Delhi, New Delhi 110016, India

Department of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia

Department of Pharmacology & Therapeutics, Roswell Park Cancer Institute, Elm Street & Carlton Street, Buffalo, New York 14263, United States

Department of Polymer-Nano Science and Technology, Jeonbuk National University, 567 Baekje-daero, Deokjin-gu, Jeonju-si 54896, Jeollabuk-do, Republic of Korea

Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea

Digital Healthcare Research Center, Institute of Information Technology and Convergence, Pukyong National University, Busan 48513, Republic of Korea

Division of Smart Healthcare, College of Information Technology and Convergence, Pukyong National University, Busan 48513, Republic of Korea

Department of Bioresources, University of Kashmir, Hazratbal, Srinagar 190006, India

Singapore-MIT Alliance for Research and Technology (SMART), Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Create Way 138602, Singapore

‘New-senior’ Oriented Smart Health Care Education Center, Pukyong National University, Busan 48513, Republic of Korea

Funding

Science and Engineering Research Board · Department of Biotechnology, Ministry of Science and Technology, India · Ministry of Education, India

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