Cobalt-Doped Fe₃O₄ Nanospheres Deposited on Graphene Oxide as Electrode Materials for Electrochemical Sensing of the Antibiotic Drug

Nanoscale materials for electrochemical detection of chloramphenicol (CAP) show a significant interest in antibiotic residue diagnostics research in food products associated with several adverse outcomes. Among various sensing materials, graphene-based materials are highly fascinating due to π–π interaction. Herein, we demonstrate the preparation of cobalt-doped Fe3O4 nanospheres deposited on graphene oxide (Co–Fe3O4 NS/GO) through a facile hydrothermal technique that was reported and then these were utilized and explored for voltammetric sensing of CAP detection in a food product. The Co–Fe3O4 NS/GO-based sensor holds a low limit of detection 1.04 nM and an excellent sensitivity of 5.0788 μA·μM–1·cm–2 with successive rapid electrode performance of selectivity, cycle stability, and reproducibility toward CAP detection. Besides, the voltammetric sensor was then successfully analyzed for CAP detection in food samples with satisfactory results. The proposed voltammetric sensor can be a low-cost effect and promising electrode material for food quality-monitoring applications.