journal article·2018-05-25

Design of Pyrrolic-N-Rich Carbon Dots with Absorption in the First Near-Infrared Window for Photothermal Therapy

Fitri A. Permatasari, Hiromitsu Fukazawa, Takashi Ogi, Ferry Iskandar, Kikuo Okuyama

ACS Applied Nano Materials· Volume 1· Issue 5
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Abstract

Pyrrolic-N-rich carbon dots (CDs) that exhibit an absorption peak in the first near-infrared (NIR) window region were developed using a one-step microwave-assisted hydrothermal synthesis. A high concentration of urea enabled the introduction of a large amount of pyrrolic-nitrogen on the CD surfaces. Upon optimization of the experimental conditions, the absorption peak of the CDs red-shifted from 550 to 650 nm. The resulting pyrrolic-N-rich CDs exhibited photothermal effects with high NIR photothermal efficiency (54.3%) and photoluminescence. The prepared CDs, which show a first NIR window absorption peak, photoluminescence, and negative surface charge, have the potential to be used as multifunctional nanocarriers for cell imaging and drug delivery and as photothermal agents in cancer therapy.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Carbon and Quantum Dots Applications · Nanocluster Synthesis and Applications · Quantum Dots Synthesis And Properties

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Chemical Engineering, Graduate School of Engineering, Hiroshima University, Higashi-Hiroshima 739-8527, Japan

Department of Physics, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Bandung 40132, Indonesia

Research Center for Nanoscience and Nanotechnology, Institut Teknologi Bandung, Bandung 40132, Indonesia

Funding

Ministry of Education, Culture, Sports, Science and Technology · Center for Functional Nano Oxide, Hiroshima University · Ministry of Research, Technology and Higher Education, Republic of Indonesia · Ministry of Finance of the Republic of Indonesia Secretariat General Indonesia Endowment Fund for Education (LPDP)

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