Fabrication of polymersomes with liposome-extracted lipid membrane preserving original leaflet asymmetry
Source abstract
Abstract
(SL14), to the liposome dispersion, and (3) applying heat treatment at 90 °C for 1 hour. Emission quenching tests of NBD tethered to the membrane surface and FRET analysis indicated that the PLHV included an independent lipid domain distinct from the peptide domain, preserving the membrane asymmetry of the original liposome within this lipid domain. Although hybrid vesicles and liposomes had similar encapsulation efficiency, hybrid vesicles showed greater storage stability due to the rigidity of the peptide domain. This technology illuminates the development of drug delivery systems utilizing natural cell membranes.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Advanced Polymer Synthesis and Characterization · Innovative Microfluidic and Catalytic Techniques Innovation
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Nano Medical Engineering Laboratory, RIKEN Cluster for Pioneering Research (CPR), 2-1 Hirosawa, Wako, Saitama 351-0198, Japan
Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0397, Japan
Emergent Bioengineering Materials Research Team, RIKEN Center for Emergent Matter Science (CEMS), 2-1 Hirosawa, Wako, Saitama 351-0198, Japan
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