journal article·2025Open access

α-Ketoglutaric acid-derived carbon nanodots doped with manganese as fluorescent and MRI contrast agents

Ioana-Andreea Turin-Moleavin, Adina Coroaba, Adrian Fifere, Narcisa Laura Marangoci, Mariana Pinteala, Cristina Mariana Uritu, Silviu Iulian Filipiuc, Marius Dobromir, Ionut Radu Tigoianu, Tudor Pinteala

Nanoscale· Volume 17· Issue 35

Abstract

-weighted contrast in MRI at clinically relevant magnetic field strengths. Fluorescence imaging demonstrated that both types of CNDs displayed strong fluorescence and high photostability, thereby confirming their potential as fluorescent probes. KGAMn-CNDs exhibited dual functionality, serving as contrast agents for fluorescence and MRI. These findings highlight the potential of KGA-derived CNDs as efficient dual-mode imaging agents and establish KGA as a versatile and innovative precursor for the development of CNDs with tunable physicochemical properties.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Carbon and Quantum Dots Applications · Nanocluster Synthesis and Applications · Lanthanide and Transition Metal Complexes

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Centre of Advanced Research in Bionanoconjugates and Biopolymers, “Petru Poni” Institute of Macromolecular Chemistry, 700487 Iasi, Romania

Advanced Center for Research and Development in Experimental Medicine “Prof. Ostin C. Mungiu”, “Grigore T. Popa” University of Medicine and Pharmacy, 700454 Iasi, Romania

Research Centre on Advanced Materials and Technologies, Department of Exact and Natural Sciences, Institute of Interdisciplinary Research, “Alexandru Ioan Cuza” University of Iasi, Faculty of Physics, 700506 Iasi, Romania

Physical Chemistry of Polymers, “Petru Poni” Institute of Macromolecular Chemistry, 700487 Iasi, Romania

Department of Orthopedics and Traumatology, Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania

Funding

Ministerul Cercetării, Inovării şi Digitalizării

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