Nucleic acid detection with single-base specificity integrating isothermal amplification and light-up aptamer probes
Source abstract
Abstract
We report a novel platform for label-free nucleic acid detection using isothermal amplification and light-up aptamer probes. This assay converts double-stranded amplicons into single-stranded targets to enable sequence-specific hybridization with split dapoxyl aptamer probes, offering attomolar sensitivity and single-base specificity.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques · Biosensors and Analytical Detection · Advanced Biosensing Techniques and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Interdisciplinary Program in Bioengineering, Seoul National University, Seoul 08826, Republic of Korea
Research Institute of Advanced Materials, Seoul National University, Seoul, 08826, Republic of Korea
Department of Materials Science and Engineering, Seoul National University, Seoul, 08826, Republic of Korea
Funding
National Research Foundation of Korea · Seoul National University
References (29)
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