journal article·2015

Increased localization precision by interference fringe analysis

Carl G. Ebeling, Amihai Meiri, Jason Martineau, Zeev Zalevsky, Jordan M. Gerton, Rajesh Menon

Nanoscale· Volume 7· Issue 23
Publisher page

Abstract

We report a novel optical single-emitter-localization methodology that uses the phase induced by path length differences in a Mach-Zehnder interferometer to improve localization precision. Using information theory, we demonstrate that the localization capability of a modified Fourier domain signal generated by photon interference enables a more precise localization compared to a standard Gaussian intensity distribution of the corresponding point-spread function. The calculations were verified by numerical simulations and an exemplary experiment, where the centers of metal nanoparticles were localized to a precision of 3 nm.
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Research context

OpenAlex topics: Advanced Fluorescence Microscopy Techniques · Force Microscopy Techniques and Applications · Near-Field Optical Microscopy

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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