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journal article·2026

An 124 I-radiolabeled exosome-based treatment platform for enhanced boron neutron capture therapy: precise delivery and real-time PET tracking of boron

Ziteng Chen, Zhijie Wang, Mingxin Yang, Ruyu Yan, Linwen Lv, Ya-nan Chang, Kui Chen, Wenjiang Yang, Hui Yuan, Xiangxi Meng, Lingbo Zhu, Zhi Yang, Gengmei Xing, Juan Li

Nanoscale· Volume 18· Issue 12
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Source abstract

Abstract

I-labeled BCDs into a large excess of unlabeled BCDs, followed by exosome encapsulation. This approach offers a practical and clinically translatable strategy for real-time treatment guidance. This study provides a generalizable technical paradigm for advancing exosome-mediated BNCT toward clinical application in gliomas.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Boron Compounds in Chemistry · Boron and Carbon Nanomaterials Research · Organoboron and organosilicon chemistry

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Laboratory for Biomedical Effects of Nanomaterial and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China

University of Chinese Academy of Sciences, Beijing 100049, China

Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing Key Laboratory of Research, Investigation and Evaluation of Radiopharmaceuticals, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing 100142, China

Spallation Neutron Source Science Center, Dongguan 523803, China

Funding

National Basic Research Program of China · Chinese Academy of Sciences

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