journal article·2026

Engineering a CeO 2 layer on gold nanopyramids for enhanced near-infrared photothermal conversion

Yifan Wang, Hong Qu, Guofeng Zhang, Wusong Geng, Lifeng Hang, Tao Zhang, Yue Li

Nanoscale· Volume 18· Issue 5
Publisher page

Abstract

Gold-based core-shell oxides show great potential in photothermal theranostics, but their applications are limited by the inability for precise regulation of light absorption. Here, we developed a type of gold bipyramid covered by a cerium oxide layer (ACH) with tunable thickness to enhance near-infrared light absorption and photothermal conversion efficiency. The anisotropic feature enabled ACH with strong light absorption at 1064 nm, accompanied by photothermal efficiency as high as 56.2%. In vitro and in vivo results demonstrated that ACH possessed capabilities for dual-modality molecular-targeted imaging and efficient tumor inhibition via photothermal therapy. Integration of the computed tomography and photoacoustic imaging capabilities of ACH nanoparticles showed real-time feedback during synergistic treatment, enabling timely monitoring and adjustment of therapeutic procedures. This work reveals the impact of metal oxide layer on the photothermal performance of plasmonic nanostructures, providing a new strategy for near-infrared theranostics.
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Research context

OpenAlex topics: Catalytic Processes in Materials Science · Transition Metal Oxide Nanomaterials · Gold and Silver Nanoparticles Synthesis and Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Key Laboratory of Materials Physics, Institute of Solid State Physics, HFIPS, Chinese Academy of Sciences, Hefei 230031, P.R. China

University of Science and Technology of China, Hefei, 230026, P.R. China

Department of Medical Imaging, Guangdong Second Provincial General Hospital, Jinan University, Guangzhou 518037, P.R. China

Department of Nuclear Medicine, The First Affiliated Hospital (Southwest Hospital) of Army Medical University, Chongqing, 400038, P.R. China

School of Physical Science and Technology, Tiangong University, No. 399 BinShuiXi Road, XiQing District, Tianjin 300387, P.R. China

School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371, Singapore

Funding

National Natural Science Foundation of China

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