journal article·2020

A ratiometric photoacoustic imaging approach for semi-quantitative determination of aggregation efficiency in vivo

Bo Peng, Xiu-Mei Liu, Hsian-Rong Tseng, Li-Li Li, Hao Wang

Nanoscale· Volume 12· Issue 36
Publisher page

Abstract

M PA probe was 58% after 2 hours of incubation. After intratumoral administration in xenografted pancreatic tumor mice, the highest aggregation efficiency was found to be 36% 6 hours after the injection. The ratiometric PA probe provides us with a real-time method to detect the aggregation efficiency in vivo, which is helpful to deepen the understanding of the dynamic assembly process and optimize the design of supramolecules.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Photoacoustic and Ultrasonic Imaging · Nanoplatforms for cancer theranostics · Photodynamic Therapy Research Studies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Laboratory for Biomedical Effects of Nanomaterials and Nanosafety

CAS Center for Excellence in Nanoscience

National Center for Nanoscience and Technology (NCNST)

Beijing

China

Crump Institute for Molecular Imaging

California NanoSystems Institute

Department for Molecular and Medical Pharmacology UCLA

Los Angeles

USA

Funding

National Natural Science Foundation of China · Youth Innovation Promotion Association of the Chinese Academy of Sciences · Chinese Academy of Sciences

References (37)

Show source-provided references
1. Zheng · ACS Appl. Mater. Interfaces · 2017 · 9 · 2118110.1021/acsami.7b05230 ↗
2. Bunce · Sci. Adv. · 2019 · 5 · eaav821610.1126/sciadv.aav8216 ↗
3. Qi · Adv. Mater. · 2018 · 30 · e170344410.1002/adma.201703444 ↗
4. Peters · Nat. Commun. · 2019 · 10 · 119110.1038/s41467-019-09081-5 ↗
5. Matson · Curr. Opin. Solid State Mater. Sci. · 2011 · 15 · 22510.1016/j.cossms.2011.08.001 ↗
6. Vauthey · Proc. Natl. Acad. Sci. U. S. A. · 2002 · 99 · 535510.1073/pnas.072089599 ↗
7. Hendricks · Acc. Chem. Res. · 2017 · 50 · 244010.1021/acs.accounts.7b00297 ↗
8. Zimenkov · J. Am. Chem. Soc. · 2006 · 128 · 677010.1021/ja0605974 ↗
9. Ye · Nat. Chem. · 2014 · 6 · 51910.1038/nchem.1920 ↗
10. Meng · Biomaterials · 2018 · 174 · 4110.1016/j.biomaterials.2018.04.056 ↗
11. Zhang · Adv. Mater. · 2015 · 27 · 612510.1002/adma.201502598 ↗
12. An · Nat. Commun. · 2019 · 10 · 486110.1038/s41467-019-12848-5 ↗
13. Wang · Chem. Soc. Rev. · 2016 · 45 · 558910.1039/C6CS00176A ↗
14. Gao · Nat. Commun. · 2012 · 3 · 103310.1038/ncomms2040 ↗
15. Zhou · J. Am. Chem. Soc. · 2014 · 136 · 297010.1021/ja4127399 ↗
16. Lovell · Nat. Mater. · 2011 · 10 · 32410.1038/nmat2986 ↗
17. Fabiano · Photochem. Photobiol. · 1997 · 66 · 33610.1111/j.1751-1097.1997.tb03156.x ↗
18. D'Anna · Chemistry · 2015 · 21 · 1478010.1002/chem.201502240 ↗
19. T. E. Barman , Enzyme Handbook , Springer , Berlin, Heidelberg , 197410.1007/978-3-662-11691-3 ↗
20. Wang · Bioconjugate Chem. · 2009 · 20 · 3210.1021/bc8001908 ↗
21. Avvakumova · Bioconjugate Chem. · 2014 · 25 · 138110.1021/bc500202b ↗
22. Li · ACS Appl. Mater. Interfaces · 2016 · 8 · 1793610.1021/acsami.6b05795 ↗
23. Meyer · Angew. Chem., Int. Ed. · 2003 · 42 · 121010.1002/anie.200390319 ↗
24. Huang · Dyes Pigm. · 2019 · 160 · 83910.1016/j.dyepig.2018.08.066 ↗
25. Würthner · Angew. Chem., Int. Ed. · 2011 · 50 · 337610.1002/anie.201002307 ↗
26. Pescitelli · J. Am. Chem. Soc. · 2003 · 125 · 761310.1021/ja030047v ↗
27. Matile · J. Am. Chem. Soc. · 1996 · 118 · 519810.1021/ja960126p ↗
28. Rajora · Chem. Soc. Rev. · 2017 · 46 · 643310.1039/C7CS00525C ↗
29. Chen · Adv. Mater. · 2015 · 27 · 682010.1002/adma.201503194 ↗
30. Miller · Photochem. Photobiol. · 1993 · 57 · 9810.1111/j.1751-1097.1993.tb02262.x ↗
31. Shamay · Nat. Mater. · 2018 · 17 · 36110.1038/s41563-017-0007-z ↗
32. Tian · ACS Nano · 2011 · 5 · 976110.1021/nn203293t ↗
33. Chen · Adv. Mater. · 2019 · 31 · 190491410.1002/adma.201904914 ↗
34. Han · Anal. Chem. · 2016 · 88 · 387210.1021/acs.analchem.6b00023 ↗
35. Chen · Adv. Mater. · 2020 · 32 · 180633110.1002/adma.201806331 ↗
36. Ni · Nano Lett. · 2019 · 19 · 31810.1021/acs.nanolett.8b03936 ↗
37. Reinhardt · J. Am. Chem. Soc. · 2018 · 140 · 101110.1021/jacs.7b10783 ↗