Direct silica coating of drug crystals for ultra-high loading
Source abstract
Abstract
To push the limit of synthetic control, we create a thin layer (5 nm) of silica on the surface of drug nanocrystals, achieving a loading content (88%) that approaches the theoretical limit. The uniform silica shell provides a tailored diffusion barrier for controlled drug release. The method can be generally applied to 11 organic crystals, including 4 drugs.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Luminescence and Fluorescent Materials · Crystallography and molecular interactions · Dendrimers and Hyperbranched Polymers
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Institute of Advanced Synthesis
School of Chemistry and Molecular Engineering
Jiangsu National Synergetic Innovation Center for Advanced Materials
Nanjing Tech University
Nanjing
Funding
National Natural Science Foundation of China · Recruitment Program of Global Experts · Jiangsu Science and Technology Department · Nanjing Tech University · Jiangsu National Synergistic Innovation Center for Advanced Materials
References (37)
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