Tandem post-synthetic modification of a zeolitic imidazolate framework for CXCR4-overexpressed esophageal squamous cell cancer imaging and therapy
Source abstract
Abstract
-weighted magnetic resonance imaging performance and CXCR4 targeting ability. With 5-Fu loading, AMD-ZIF-7(Mn)/5-Fu showed a synergistic therapeutic effect in DNA damage and CXCR4 inhibition of esophageal squamous cell cancer. Therefore, we propose a structural reconstruction method to effectively explore and improve the biomedical application of ZIFs in esophageal squamous cell cancer theranostics.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Metal-Organic Frameworks: Synthesis and Applications · Nanoplatforms for cancer theranostics · Esophageal Cancer Research and Treatment
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Cixi Institute of Biomedical Engineering
CAS Key Laboratory of Magnetic Materials and Devices
Zhejiang Engineering Research Center for Biomedical Materials
Ningbo Institute of Materials Technology and Engineering
Chinese Academy of Sciences
Department of Clinical Laboratory
the Affiliated Hospital of Medical School of Ningbo University
Ningbo University School of Medicine
Ningbo
P.R. China
Funding
National Basic Research Program of China · National Natural Science Foundation of China · Youth Innovation Promotion Association of the Chinese Academy of Sciences
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