Opening of DNA double helix at room temperature: Application of α-cyclodextrin self-aggregates
Source abstract
Abstract
Self-aggregation of alpha-cyclodextrin (alpha-CD) can induce DNA opening at room temperature (25 degrees C) owing to the hydroxyl groups on the surface of the spherical aggregates of alpha-CD, which promote hydrogen bonding with the flipped-out bases in DNA duplex prohibiting them from reverting back.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: RNA Interference and Gene Delivery · DNA and Nucleic Acid Chemistry · Advanced biosensing and bioanalysis techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (24)
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