journal article·2026

Novel iron–nickel bimetallic nanozyme with peroxidase-like activity for ultrasensitive uric acid detection and hyperuricaemia therapy evaluation

Hanbing Yao, Yifu Li, Yujuan Zhan, Binyu Xiao, Jiayi Yan, Shuangshuang Liu, Zimo Chen, Chang Shu

Nanoscale· Volume 18· Issue 1
Publisher page

Abstract

Ni-NFs in UA detection and hyperuricemia management, suggesting broad applications in drug development and precision medicine. This work provided mechanistic insights into bimetallic nanozymes' POD-like activity and underscores their potential for biomedical applications, offering a new strategy for hyperuricemia diagnosis and treatment.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Advanced Nanomaterials in Catalysis · Carbon and Quantum Dots Applications · Advanced biosensing and bioanalysis techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Pharmaceutical Analysis, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China

Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University), Ministry of Education, Nanjing 210009, China

Funding

Ministry of Education of the People's Republic of China

References (45)

Show source-provided references
1. Miake · Biomedicines · 2023 · 11 · 125810.3390/biomedicines11051258 ↗
2. Guo · Phytomedicine · 2023 · 116 · 15486810.1016/j.phymed.2023.154868 ↗
3. Wei-Yun · Food Agric. Immunol. · 2021 · 32 · 77810.1080/09540105.2021.1996540 ↗
4. Wang · Anal. Bioanal. Chem. · 2019 · 411 · 94310.1007/s00216-018-1524-6 ↗
5. Cheng · Hypertension · 2018 · 71 · 6610.1161/HYPERTENSIONAHA.117.10443 ↗
6. Major · Nat. Rev. Rheumatol. · 2018 · 14 · 34110.1038/s41584-018-0004-x ↗
7. Dalbeth · Lancet · 2016 · 388 · 203910.1016/S0140-6736(16)00346-9 ↗
8. Liu · Nat. Commun. · 2025 · 16 · 233910.1038/s41467-025-56100-9 ↗
9. Iseki · Hypertens. Res. · 2001 · 24 · 69110.1291/hypres.24.691 ↗
10. Sheng · Talanta · 2017 · 166 · 26810.1016/j.talanta.2017.01.066 ↗
11. Matsumoto · Carbohydr. Res. · 2012 · 358 · 8210.1016/j.carres.2012.06.018 ↗
12. Xu · J. Electroanal. Chem. · 2019 · 841 · 12910.1016/j.jelechem.2019.04.028 ↗
13. Donadio · J. Nephrol. · 2014 · 27 · 331
14. Cao · Microchem. J. · 2024 · 204 · 11107910.1016/j.microc.2024.111079 ↗
15. Fanguy · Electrophoresis · 2002 · 23 · 76710.1002/1522-2683(200203)23:5<767::AID-ELPS767>3.0.CO;2-8 ↗
16. Xie · Anal. Chem. · 2021 · 93 · 491610.1021/acs.analchem.0c05191 ↗
17. Yao · Biomed. Chromatogr. · 2007 · 21 · 52010.1002/bmc.787 ↗
18. Buckberry · Am. J. Biol. Anthropol. · 2024 · 184 · e2493810.1002/ajpa.24938 ↗
19. Zhang · Acc. Mater. Res. · 2021 · 2 · 53410.1021/accountsmr.1c00074 ↗
20. Bilal · Colloids Surf., B · 2023 · 221 · 11295010.1016/j.colsurfb.2022.112950 ↗
21. Manea · Angew. Chem., Int. Ed. · 2004 · 43 · 616510.1002/anie.200460649 ↗
22. Gao · Nat. Nanotechnol. · 2007 · 2 · 57710.1038/nnano.2007.260 ↗
23. Chen · Nat. Commun. · 2021 · 12 · 337510.1038/s41467-021-23737-1 ↗
24. Li · J. Colloid Interface Sci. · 2022 · 623 · 78710.1016/j.jcis.2022.05.059 ↗
25. Chen · Chem. Eng. J. · 2023 · 471 · 14464910.1016/j.cej.2023.144649 ↗
26. Marciniec · Chem. Rev. · 2022 · 122 · 399610.1021/acs.chemrev.1c00417 ↗
27. Feng · J. Colloid Interface Sci. · 2024 · 663 · 57710.1016/j.jcis.2024.02.160 ↗
28. Sheng · Adv. Mater. · 2024 · 36 · e221121010.1002/adma.202211210 ↗
29. Yang · Chem. Eng. J. · 2024 · 487 · 15061210.1016/j.cej.2024.150612 ↗
30. Zhu · Adv. Compos. Hybrid Mater. · 2023 · 6 · 14210.1007/s42114-023-00719-z ↗
31. Zhu · Chem. Eng. J. · 2024 · 482 · 14858910.1016/j.cej.2024.148589 ↗
32. Gu · ACS Appl. Nano Mater. · 2024 · 7 · 2468310.1021/acsanm.4c04563 ↗
33. Li · Energy Environ. Sci. · 2021 · 14 · 189710.1039/D0EE03697H ↗
34. Mu · Sens. Actuators, B · 2023 · 394 · 13442210.1016/j.snb.2023.134422 ↗
35. Zhang · Biosens. Bioelectron. · 2022 · 196 · 11371810.1016/j.bios.2021.113718 ↗
36. He · Chem. Eng. J. · 2020 · 382 · 12282510.1016/j.cej.2019.122825 ↗
37. Zhu · ACS Nano · 2023 · 17 · 683310.1021/acsnano.3c00423 ↗
38. Mu · ACS Sustainable Chem. Eng. · 2022 · 10 · 298410.1021/acssuschemeng.1c07975 ↗
39. Li · Nano Res. · 2021 · 14 · 468910.1007/s12274-021-3406-z ↗
40. Zhang · Anal. Chim. Acta · 2023 · 1279 · 34178810.1016/j.aca.2023.341788 ↗
41. Fang · Adv. Funct. Mater. · 2020 · 30 · 191008510.1002/adfm.201910085 ↗
42. Barrientos · Eur. Heart J. · 2020 · 41 · ehz872.09710.1093/ehjci/ehz872.097 ↗
43. Okafor · Pharmacol. Ther. · 2017 · 172 · 13910.1016/j.pharmthera.2016.12.004 ↗
44. Kang · Eur. Heart J. · 2021 · 42 · 457810.1093/eurheartj/ehab619 ↗
45. Yan · Arthritis Rheumatol. · 2022 · 74 · 201510.1002/art.42266 ↗