Liquid crystal-mediated self-assembly of copper nanoclusters with induced circular dichroism and amplified circularly polarized luminescence

-octylphenyl ether (TX-100) LCs were constructed and systematically investigated. The results showed that the introduction of G-SH-Cu NCs into TX-100 LCs induced the generation of supramolecular chirality. More interestingly, the circular dichroism (CD) handedness can be controlled by changing the amount of TX-100 or G-SH-Cu NCs; when the ratio of G-SH-Cu NCs and TX-100 was proportionally matched, the strength of the noncovalent interactions was sufficient to induce chiral inversion. Meanwhile, TX-100 LCs provide effective confinement of G-SH-Cu NCs, which improves the expression of asymmetry at the aggregation level and induces a 2-fold enhancement of the circularly polarized luminescence (CPL) signal. This work realizes the spatial amplification of chirality through dopants in LCs, which provides an effective method for accurately regulating the supramolecular chirality of metal NCs in the LC phase.