Simultaneous formation of helical and sheet-like assemblies from short azapeptides enables spontaneous resolution
Source abstract
Abstract
'-phenylthiourea. While N-H⋯SC/OC hydrogen bonds between the β-turn scaffolds afford a 2D pleated sheet-like structure, the head-to-tail C-I⋯π halogen bonds, together with the N-H⋯OC hydrogen bonds, support a 1D helical-like assembly, serving as linkers to connect the 2D sheet-like structures into a 3D superstructure. The two biomimetic assembly modes share the N-H⋯OC hydrogen bonds and can allow 3D homochiral elongation, driving spontaneous resolution of the short azapeptides to generate conglomerate crystals.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Chemical Synthesis and Analysis · Supramolecular Self-Assembly in Materials · Surface Chemistry and Catalysis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Chemistry, College of Chemistry and Chemical Engineering, The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, and iChEM, Xiamen University, Xiamen 361005, China
Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian 361102, China
Funding
National Natural Science Foundation of China · Natural Science Foundation of Fujian Province · Xiamen University · Fundamental Research Funds for the Central Universities
References (47)
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