journal article·2021Open access

Nanocomplex made up of antimicrobial metallo-supramolecules and model biomembranes – characterization and enhanced fluorescence

Chung-Hao Liu, Heng Wang, Lin Yang, Yun Liu, Xiaopeng Li, Mu-Ping Nieh

Nanoscale· Volume 13· Issue 35

Abstract

-3-phospho-(1'-rac-glycerol) lipid, forming a well-defined nanocomplex. Structural characterization performed by very small angle neutron scattering, small angle X-ray scattering and transmission electron microscopy suggests that the hexagonal prisms are preferably located at the rim of bicellar discs with the hexagonal face in parallel with the bilayers, instead of face-to-face stacking. Such a configuration reduces the π-π interaction and consequently enhances the fluorescence emission. Since novel supramolecules were reported to have antibiotic functions, this study provides insight into the interactions of antimicrobial supermolecules with lipid membranes, leading to potential theranostic applications.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Supramolecular Self-Assembly in Materials · Luminescence and Fluorescent Materials · Molecular Sensors and Ion Detection

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Polymer Program, Institute of Material Science, University of Connecticut, Storrs, Connecticut 06269, USA

College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518055, China

National Synchrotron Light Source – II, Brookhaven National Laboratory, Upton, New York 11973, USA

Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA

Chemical & Biomolecular Engineering Department, University of Delaware, Newark, Delaware 19716, USA

Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, Connecticut 06269, USA

Funding

National Institutes of Health · National Institute of General Medical Sciences · Biological and Environmental Research · U.S. Department of Energy · Brookhaven National Laboratory · National Institute of Standards and Technology · National Science Foundation

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