Iron oxide nanoparticles as a drug carrier reduce host immunosuppression for enhanced chemotherapy
Source abstract
Abstract
T lymphocytes more than free MTX. The complexes effectively restored the host immune system and exhibited a better anticancer efficacy than free MTX. It was worth noting that the BSA-inspired IONPs were a satisfactory contrast agent for magnetic resonance imaging of tumors and lymph nodes. Our work provides a novel strategy for enhanced chemotherapy with low levels of immunosuppression in the treatment of breast cancer and other cancers.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Nanoparticle-Based Drug Delivery · Nanoplatforms for cancer theranostics · Graphene and Nanomaterials Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Biomedical Engineering, College of Engineering, Shantou University, Shantou, 515063, China
Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma 73019, USA
College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, 518060, China
Department of Thyroid and Breast Surgery, Clinical Research Center, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515000, China
Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, 73104, USA
Funding
Li Ka Shing Foundation · National Natural Science Foundation of China · Natural Science Foundation of Guangdong Province · Foundation for the National Institutes of Health · Oklahoma Center for the Advancement of Science and Technology
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