journal article·2022Open access

Incorporating zeolitic-imidazolate framework-8 nanoparticles into kidney scaffolds: a first step towards innovative renal therapies

Fátima Guerrero, Victoria Pulido, Said Hamad, Pedro Aljama, Alejandro Martín-Malo, Carolina Carrillo-Carrión

Nanoscale· Volume 14· Issue 47

Abstract

We demonstrate for the first time the potential of zeolitic-imidazolate framework-8 nanoparticles to be incorporated within a renal scaffold while retaining their ability to remove uremic toxins (mainly hydrophobic toxins like p-cresol) under flow conditions. This work may pave the way for the future development of novel adsorbents for dialysis and/or artificial kidneys.
Source: europepmc · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Dialysis and Renal Disease Management · Neurological and metabolic disorders · Acute Kidney Injury Research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, 14004 Córdoba, Spain

Department of Medicine, University of Cordoba, 14004 Córdoba, Spain

Department of Physical, Chemical and Natural Systems, University Pablo de Olavide, 41013 Seville, Spain

Nephrology Unit, Reina Sofia University Hospital, 14004 Córdoba, Spain

Spanish Renal Research Network, Institute of Health Carlos III, 28040 Madrid, Spain

Institute for Chemical Research (IIQ), CSIC-University of Seville, 41092 Sevilla, Spain

Department of Organic Chemistry, Faculty of Chemistry, University of Seville, 41012 Seville, Spain

Funding

Agencia Estatal de Investigación · Instituto de Salud Carlos III · Consejería de Salud y Familias, Junta de Andalucía · Ministerio de Ciencia e Innovación

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