Immunomodulatory properties of carbon nanotubes are able to compensate immune function dysregulation caused by microgravity conditions
Source abstract
Abstract
Spaceflights lead to dysregulation of the immune cell functionality affecting the expression of activation markers and cytokine production. Short oxidized multi-walled carbon nanotubes functionalized by 1,3-dipolar cycloaddition have been reported to activate immune cells. In this Communication we have performed surface marker assays and multiplex ELISA on primary monocytes and T cells under microgravity. We have discovered that carbon nanotubes, through their immunostimulatory properties, are able to fight spaceflight immune system dysregulations.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Spaceflight effects on biology · Medical and Biological Ozone Research · Anesthesia and Neurotoxicity Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Dipartimento di Scienze Biomediche
Università degli studi di Sassari
07100 Sassari, Italy
Dipartimento di Chimica e Farmacia
Università degli Studi di Sassari
CNRS
Institut de Biologie Moléculaire et Cellulaire
Laboratoire d'Immunopathologie et Chimie Thérapeutique
, France
Dipartimento di Medicina Clinica
Sperimentale e Oncologica Università degli Studi di Sassari
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