Tumor targeted micellar nanocarriers assembled from epipodophyllotoxin-based amphiphiles
Source abstract
Abstract
Micelle-forming amphiphilic drug conjugates were synthesized starting from a biologically active epipodophyllotoxin derivative which was covalently inserted in between a hydrophilic PEG unit and a hydrophobic stearyl chain. The epipodophyllotoxin-containing amphiphiles were assembled into the corresponding micelles which were evaluated in vivo for their tumor targeting properties.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Dendrimers and Hyperbranched Polymers · Nanoparticle-Based Drug Delivery · Porphyrin and Phthalocyanine Chemistry
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Service de Chimie Bioorganique et de Marquage (SCBM)
CEA
Université Paris-Saclay
91191 Gif-sur-Yvette
France
Molecular Imaging Research Center (MIRCen)
UMR 9199
92265 Fontenay-aux-Roses
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