7-Methylguanine Traps PARP-1 on Nucleosomes: spFRET Microscopy Study
Source abstract
Abstract
nucleosomes (Figs. 1 C, D). Moreover, 7-MG blocks NAD-induced dissociation of PARP-1 from the complexes with nucleosomes, thus trapping the enzyme on nucleosomes (Figs.
Only a short abstract or summary was supplied by the source.
Source: openalex_inverted_index · Quality: short
Research context
OpenAlex topics: PARP inhibition in cancer therapy · Advanced Electron Microscopy Techniques and Applications · DNA Repair Mechanisms
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References (11)
Show source-provided references
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3. Financial supported by RFBR grant № 17-00-00163 (17-00-00132, 17-00-00097) is acknowledged.
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