HBV Core-Directed Antivirals and Importin β Can Synergistically Disrupt Capsids
Source abstract
Abstract
Christine Kim, Christopher Schlicksup, Lauren Barnes, Martin Jarrold, Angela Patterson, Brian Bothner, Adam Zlotnick; HBV Core-Directed Antivirals and Impo
Only a short abstract or summary was supplied by the source.
Source: openalex_inverted_index · Quality: short
Research context
OpenAlex topics: Hepatitis B Virus Studies · Hepatitis Viruses Studies and Epidemiology · Viral Infections and Outbreaks Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (7)
Show source-provided references
1. Nuclear import of hepatitis B virus capsids and release of the viral genome10.1073/pnas.1730940100 ↗
2. Small-Molecule Effectors of Hepatitis B Virus Capsid Assembly Give Insight into Virus Life Cycle10.1128/JVI.01360-08 ↗
3. [1] Hepatitis, B. World Health Organization (2018). at < http://www.who.int/news-room/fact-sheets/detail/hepatitis-b >.
4. Discovery of Small Molecule Therapeutics for Treatment of Chronic HBV Infection10.1021/acsinfecdis.7b00144 ↗
5. HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways10.1371/journal.ppat.1006658 ↗
6. The Structural Biology of Hepatitis B Virus: Form and Function
7. Importin β Can Bind Hepatitis B Virus Core Protein and Empty Core-Like Particles and Induce Structural Changes10.1371/journal.ppat.1005802 ↗