Biomimetic Scaffolds for Tendon Tissue Regeneration
Source abstract
Abstract
Tendon tissue connects muscle to bone and plays crucial roles in stress transfer. Tendon injury remains a significant clinical challenge due to its complicated biological structure and poor self-healing capacity. The treatments for tendon injury have advanced significantly with the development of technology, including the use of sophisticated biomaterials, bioactive growth factors, and numerous stem cells. Among these, biomaterials that the mimic extracellular matrix (ECM) of tendon tissue would provide a resembling microenvironment to improve efficacy in tendon repair and regeneration. In this review, we will begin with a description of the constituents and structural features of tendon tissue, followed by a focus on the available biomimetic scaffolds of natural or synthetic origin for tendon tissue engineering. Finally, we will discuss novel strategies and present challenges in tendon regeneration and repair.
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Research context
OpenAlex topics: Tendon Structure and Treatment · Electrospun Nanofibers in Biomedical Applications · Laser Applications in Dentistry and Medicine
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Savaid Stomatology, Hangzhou Medical College, Hangzhou 310000, China
School of Basic Medical Sciences and Forensic Medicine, Hangzhou Medical College, Hangzhou 310000, China
School of Pharmacy, Hangzhou Medical College, Hangzhou 310000, China
School of Medical Imaging, Hangzhou Medical College, Hangzhou 310000, China
Department of Biomedical Engineering, College of Biology, Hunan University, Changsha 410082, China
Funding
National Innovation and Entrepreneurship Training Program for College Students · Science and Technological Innovation Project for College Students in Zhejiang Province
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