Electrochemical and in vitro bioactivity behavior of poly (ε-caprolactone) (PCL)-gelatin-forsterite nano coating on titanium for biomedical application
Source abstract
Abstract
Abstract In this study, in order to improve the biological, chemical, and mechanical properties of titanium, poly (e-caprolactone) (PCL) - Gelatin (Gel) - forsterite nano composite coating is performed on the titanium substrates. First, a uniform suspension of PCL-Gel-forsterite nano composite was prepared and then, titanium substrates were dip coated in it and then an individual nanofiber coating was employed on the first layer coating via electrospinning method. The characterization of PCL-Gel-forsterite nano composite coated samples was determined through scanning electron microscopy (SEM), X-ray diffraction (XRD). The outcome indicates a uniform nanofibrous coating containing 2 wt % forsterite nanoparticles and various amounts of the PCL were produced. The corrosion resistance of the ceramic-polymer nano fibrous coating was investigated in phosphate buffered saline solution (PBS) using electrochemical impedance spectroscopy (EIS) and it is proved that the nanofibrous coating significantly improve the corrosion resistance of the titanium substrate. At the end the cellular responses of produced nanofibers to MG63 cells were evaluated and cell viability results showed that bioactivity improved with decreasing GEL content confirming the potential application of PCL-Gel-forsterite nanofibrous composite coating for biomedical applications.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Bone Tissue Engineering Materials · Tissue Engineering and Regenerative Medicine
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (59)
Show source-provided references
1. Effects of surface modification on the mechanical and structural properties of nanofibrous poly (ε-caprolactone)/forsterite scaffold for tissue engineering applications10.1016/j.msec.2013.07.002 ↗
2. Corrosion resistance and cytocompatibility studies of zinc-doped fluorohydroxyapatite nanocomposite coatings on titanium implant10.1016/j.ceramint.2015.09.160 ↗
3. Covalent immobilization of enoxacin onto titanium implant surfaces for inhibiting multiple bacterial species infection and in vivo methicillin-resistant Staphylococcus aureus infection prophylaxis
4. In-situ preparation of scholzite conversion coatings on titanium and Ti-6Al-4V for biomedical applications10.1016/j.colsurfb.2017.03.007 ↗
5. Pectin nanocoating of titanium implant surfaces‐an experimental study in rabbits10.1111/clr.12798 ↗
6. Nanoscale surface modification by anodic oxidation increased bone ingrowth and reduced fibrous tissue in the porous coating of titanium–alloy femoral hip arthroplasty implants10.1002/jbm.b.33554 ↗
7. Assessment of a polyelectrolyte multilayer film coating loaded with BMP-2 on titanium and PEEK implants in the rabbit femoral condyle10.1016/j.actbio.2016.03.010 ↗
8. Influence of polyetheretherketone coatings on the Ti–13Nb–13Zr titanium alloy’s bio-tribological properties and corrosion resistance10.1016/j.msec.2016.02.043 ↗
9. Oxidation resistance and mechanical properties of HfC nanowire-toughened ultra-high temperature ceramic coating for SiC-coated C/C composites10.1016/j.apsusc.2015.11.097 ↗
10. Osseointegration is improved by coating titanium implants with a nanostructured thin film with titanium carbide and titanium oxides clustered around graphitic carbon10.1016/j.msec.2016.08.076 ↗
11. Tribological, electrochemical and in vitro biocompatibility properties of SiC reinforced composite coatings10.1016/j.matdes.2016.01.143 ↗
12. Glass-based coatings on biomedical implants: a state-of-the-art review10.1515/bglass-2017-0001 ↗
13. In vitro and in vivo degradation evaluation of novel iron-bioceramic composites for bone implant applications10.1016/j.msec.2013.12.022 ↗
14. Biosilicate scaffolds for bone regeneration: influence of introducing SrO10.1039/C7RA01606A ↗
15. Synthesis and characterization of nanocrystalline forsterite coated poly (l-lactide-co-β-malic acid) scaffolds for bone tissue engineering applications10.1016/j.msec.2015.01.005 ↗
16. Sr-doped forsterite nanopowder: synthesis and biological properties10.1016/j.ceramint.2017.06.054 ↗
17. Effect of forsterite addition on the densification and properties of hydroxyapatite bioceramic
18. Biomimetic collagen–hydroxyapatite composite fabricated via a novel perfusion-flow mineralization technique10.1089/ten.tec.2012.0452 ↗
19. Rapid densification of forsterite ceramic via microwave sintering
20. Effects of surface modification on the mechanical and structural properties of nanofibrous poly (ε-caprolactone)/forsterite scaffold for tissue engineering applications10.1016/j.msec.2013.07.002 ↗
21. The synthesis and properties of high-quality forsterite ceramics using desert drift sands to replace traditional raw materials10.2109/jcersj2.16268 ↗
22. Physicochemical and antifungal properties of bio-nanocomposite film based on gelatin-chitin nanoparticles10.1016/j.ijbiomac.2016.12.066 ↗
23. Electrodeposition of chitosan/gelatin/nanosilver: a new method for constructing biopolymer/nanoparticle composite films with conductivity and antibacterial activity10.1016/j.msec.2015.04.031 ↗
24. Physical and antioxidant properties of films based on gelatin, gelatin-chitosan or gelatin-sodium caseinate blends loaded with nanoemulsified active compounds10.1016/j.jfoodeng.2017.05.023 ↗
25. In vitro study of nano-hydroxyapatite/chitosan–gelatin composites for bio-applications10.1016/j.jare.2013.02.004 ↗
26. Gelatin–nanogold bioconjugates as effective plasmonic platforms for SERS detection and tagging10.1016/j.colsurfb.2012.10.046 ↗
27. Synergistic gelation of gelatin B with xanthan gum10.1016/j.foodhyd.2016.03.043 ↗
28. Preparation and characterization of crosslinked chitosan/gelatin scaffolds by ice segregation induced self-assembly10.1016/j.carbpol.2015.12.064 ↗
29. In vivo performance of novel soybean/gelatin-based bioactive and injectable hydroxyapatite foams10.1016/j.actbio.2014.10.034 ↗
30. Deposition of microarc oxidation–polycaprolactone duplex coating to improve the corrosion resistance of magnesium for biodegradable implants10.1016/j.tsf.2014.04.004 ↗
31. Significant degradability enhancement in multilayer coating of polycaprolactone-bioactive glass/gelatin-bioactive glass on magnesium scaffold for tissue engineering applications10.1016/j.apsusc.2015.02.120 ↗
32. Deposition of nanostructured fluorine-doped hydroxyapatite–polycaprolactone duplex coating to enhance the mechanical properties and corrosion resistance of Mg alloy for biomedical applications10.1016/j.msec.2015.11.057 ↗
33. “In-vitro” corrosion behaviour of the magnesium alloy with Al and Zn (AZ31) protected with a biodegradable polycaprolactone coating loaded with hydroxyapatite and cephalexin10.1016/j.electacta.2015.04.013 ↗
34. Corrosion and bioactivity evaluation of nanocomposite PCL-forsterite coating applied on 316L stainless steel10.1016/j.surfcoat.2016.08.094 ↗
35. Enhanced corrosion resistance and biocompatibility of AZ31 Mg alloy using PCL/ZnO NPs via electrospinning10.1016/j.apsusc.2016.10.092 ↗
36. Evaluation of electrospun PLLA/PEGDMA polymer coatings for vascular stent material10.1080/09205063.2016.1176715 ↗
37. Osteoblast response on co-modified titanium surfaces via anodization and electrospinning10.1016/j.apsusc.2013.09.168 ↗
38. Potential of electrospun nanofibers for biomedical and dental applications10.3390/ma9020073 ↗
39. Tailoring degradation of AZ31 alloy by surface pre-treatment and electrospun PCL fibrous coating10.1016/j.msec.2016.04.017 ↗
40. Electrospun collagen mimicking the reconstituted extracellular matrix improves osteoblastic differentiation onto titanium surfaces10.1166/jnn.2013.7195 ↗
41. Preparation of gentamicin-loaded electrospun coating on titanium implants and a study of their properties in vitro10.1007/s00402-012-1490-y ↗
42. Electrospun vancomycin-loaded coating on titanium implants for the prevention of implant-associated infections
43. The significance of electrospinning as a method to create fibrous scaffolds for biomedical engineering and drug delivery applications10.1016/j.jddst.2015.12.007 ↗
44. Dipyridamole embedded in Polycaprolactone fibers prepared by coaxial electrospinning as a novel drug delivery system10.1016/j.jddst.2015.07.001 ↗
45. Electrochemical and in vitro bioactivity of nanocomposite gelatin-forsterite coatings on AISI 316 L stainless steel10.1016/j.porgcoat.2016.11.029 ↗
46. Effect of surface roughness on osteogenesis in vitro and osseointegration in vivo of carbon fiber-reinforced polyetheretherketone–nanohydroxyapatite composite
47. Human mesenchymal stem cell viability, proliferation and differentiation potential in response to ceramic chemistry and surface roughness10.1016/j.ceramint.2015.01.110 ↗
48. Incorporation of nanohydroxyapatite and vitamin D3 into electrospun PCL/Gelatin scaffolds: the influence on the physical and chemical properties and cell behavior for bone tissue engineering10.1002/pat.4134 ↗
49. Fabrication and characterization of electrospun polycaprolactone and gelatin composite cuffs for tissue engineered blood vessels10.1002/jbm.b.33871 ↗
50. Antibacterial activity of gelatin/copper (II)-exchanged montmorillonite films10.1016/j.foodhyd.2016.10.030 ↗
51. Development of novel aligned nanofibrous composite membranes for guided bone regeneration10.1016/j.jmbbm.2013.03.025 ↗
52. Beaded nanofibers formed during electrospinning10.1016/S0032-3861(99)00068-3 ↗
53. Electrospun PCL/HA coated friction stir processed AZ31/HA composites for degradable implant applications10.1016/j.jmatprotec.2017.10.009 ↗
54. Inhibition of the pitting corrosion of 304 stainless steel in 0.5 M hydrochloric acid solution by heptamolybdate ions10.1016/j.corsci.2014.10.023 ↗
55. Electrochemical investigation of stainless steel corrosion in a proton exchange membrane electrolyzer cell10.1016/j.ijhydene.2015.07.061 ↗
56. Superhydrophobic aluminum alloy surfaces prepared by chemical etching process and their corrosion resistance properties10.1016/j.apsusc.2015.08.166 ↗
57. An improvement in corrosion resistance of 316L AISI coated using PCL-gelatin composite by dip-coating method10.1016/j.porgcoat.2019.01.057 ↗
58. Chitosan-58S bioactive glass nanocomposite coatings on TiO2 nanotube: structural and biological properties10.1016/j.apsusc.2018.01.314 ↗
59. Anisotropic architecture and electrical stimulation enhance neuron cell behaviour on a tough graphene embedded PVA: alginate fibrous scaffold10.1039/C7RA13136D ↗