Distinct Roles of Matrigel Enabled the Production of Expandable Hepatoblast and Polarized Hepatocyte Organoids from Human Embryonic Stem Cells under 3-Dimensional Suspension Conditions
Abstract
Research context
OpenAlex topics: Liver physiology and pathology
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Affiliations
Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510006, China.
Laboratory of Stem Cells and Translational Medicine, Center for Medical Research on Innovation and Translation, Institute of Clinical Medicine, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510006, China.
Laboratory of Stem Cells and Translational Medicine, Institute for Life Science, School of Medicine, South China University of Technology, Guangzhou 510006, China.
School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou 511442, China.
Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People’s Hospital, Guangzhou 510180, China.
Surgical Department of Hepatobiliary Pancreas and Spleen, Affiliated Chinese Medicine Hospital at Tianhe Campus, Guangzhou Medical University, Guangzhou 510645, China.
National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, China.
The Innovation Centre of Ministry of Education for Development and Diseases, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510006, China.
Funding
National Key Research and Development Program of China grant · Research Starting Funding of South China University of Technology · Research Starting Funding of the Second Affiliated Hospital of South China University of Technology · Research Agreement between South China University of Technology and Guangzhou First People’s Hospital · Guangdong Basic and Applied Basic Research Foundation